Zhang Xin, Kang Xiaokui, Jiang Qunlong, Zhao Hua, Tang Yinda, Zhu Jin, Zhou Ping, Yuan Yan, Li Shiting
Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Center for Diagnosis and Treatment of Cranial Nerve Diseases, Shanghai Jiao Tong University, Shanghai, China.
Department of Neurosurgery, Liaocheng People's Hospital, Liaocheng, Shandong, China.
World Neurosurg. 2018 Feb;110:e473-e478. doi: 10.1016/j.wneu.2017.11.022. Epub 2017 Nov 14.
Microvascular decompression (MVD) is useful treatment for hemifacial spasm (HFS) with refractory hypertension (RHTN). The biomedical glue sling technique is a new method for MVD. In this study, we retrospectively compared the outcome of the biomedical glue sling technique with traditional technique in MVD for HFS with RHTN.
A retrospective study of HFS with RHTN treated by MVD was conducted between January 2010 and June 2016. Among 155 patients who underwent their first MVD at our institution, traditional technique was performed in 73 cases of patients and the biomedical glue sling technique was performed on 82 patients.
At 3 days, 7 days, 1 month, 3 months, and 1 year after MVD surgery, in the traditional technique group the effective rates of MVD for HFS were 86.30%, 84.93%, 87.14%, 84.06%, and 83.33%. The effective rates for RHTN were 68.49%, 67.12%, 65.71%, 57.97%, and 57.58%. The incidence rates of complication were 5.48%, 5.48%, 4.29%, 2.90%, and 3.03%. In the biomedical glue sling technique group, the effective rates of MVD for HFS were 97.56%, 97.56%, 98.75%, 96.15%, and 94.59% (P < 0.05). The effective rates for RHTN were 85.37%, 82.93%, 81.25%, 79.49%, and 75.68% (P < 0.05). The incidence rates of complication were 6.10%, 6.10%, 5.00%, 3.85%, and 2.70% (P > 0.05).
When HFS is associated with RHTN, the efficacy of the biomedical glue sling technique for MVD is higher than that of the traditional technique for both HFS and RHTN.
微血管减压术（MVD）是治疗伴有难治性高血压（RHTN）的面肌痉挛（HFS）的有效方法。生物医学胶水悬吊技术是一种新的微血管减压术方法。在本研究中，我们回顾性比较了生物医学胶水悬吊技术与传统技术在治疗伴有RHTN的HFS的微血管减压术中的效果。
对2010年1月至2016年6月间接受微血管减压术治疗的伴有RHTN的HFS患者进行回顾性研究。在我院首次接受微血管减压术的155例患者中，73例采用传统技术，82例采用生物医学胶水悬吊技术。
微血管减压术后3天、7天、1个月、3个月和1年，传统技术组中微血管减压术治疗HFS的有效率分别为86.30%、84.93%、87.14%、84.06%和83.33%。治疗RHTN的有效率分别为68.49%、67.12%、65.71%、57.97%和57.58%。并发症发生率分别为5.48%、5.48%、4.29%、2.90%和3.03%。在生物医学胶水悬吊技术组中，微血管减压术治疗HFS的有效率分别为97.56%、97.56%、98.75%、96.15%和94.59%（P<0.05）。治疗RHTN的有效率分别为85.37%、82.93%、81.25%、79.49%和75.68%（P<0.05）。并发症发生率分别为6.10%、6.10%、5.00%、3.85%和2.70%（P>0.05）。
当HFS伴有RHTN时，生物医学胶水悬吊技术在微血管减压术中治疗HFS和RHTN的疗效均高于传统技术。
