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腹膜后炎性肌纤维母细胞瘤:病例报告及免疫组织化学研究

Retroperitoneal Inflammatory Myofibroblastic Tumor: Case Report and Immunohistochemistry Study.

作者信息

Ziadi Sonia, Trimeche Mounir, Mestiri Sarra, Joma Wafa, Mokni Moncef, Lataif Rached, Sriha Badreddine, Korbi Sadok

机构信息

Departments of Pathology, CHU Farhat-Hached, Tunisia.

Departments of Surgery, CHU Farhat-Hached, Tunisia.

出版信息

World J Oncol. 2010 Apr;1(2):94-96. doi: 10.4021/wjon2010.03.192w. Epub 2010 Apr 30.

Abstract

Inflammatory myofibroblastic tumors (IMT) are a rare clinicopathological entity of yet unknown etiology and those located retroperitoneally are even rarer. Clinical outcome is unpredictable and complete surgical resection of the tumor remains the principal treatment. We report the case of a 41-year old man presented with abdominal pain. An abdominal magnetic resonance imaging scan revealed a retroperitoneal tumor located between the pancreas, stomach small curvature and big vessels. A laparotomy with biopsy was performed because the tumor was not amenable to surgical resection. Histopathological examination concluded to an IMT with overexpression of protein p53. Epstein-Barr virus and Human Herpesvirus-8 investigation was negative. Postoperative outcome was unfavorable.

摘要

炎性肌纤维母细胞瘤(IMT)是一种病因不明的罕见临床病理实体,而位于腹膜后的IMT更为罕见。临床结果不可预测,肿瘤的完整手术切除仍然是主要治疗方法。我们报告一例41岁男性,因腹痛就诊。腹部磁共振成像扫描显示腹膜后肿瘤位于胰腺、胃小弯和大血管之间。由于肿瘤无法进行手术切除,故行剖腹活检术。组织病理学检查结果为IMT伴蛋白p53过表达。爱泼斯坦-巴尔病毒和人类疱疹病毒8检测均为阴性。术后结果不佳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/5649911/098db5072761/wjon-01-094-g001.jpg

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