Rossi David, Giordani Paolo, Alessandroni Paolo, Catalano Vincenzo, Casadei Virginia, Baldelli Anna Maria, Fedeli Stefano Luzi, Graziano Francesco, Fiorentini Giammaria
Azienda Ospedaliera "Ospedali Riuniti Marche Nord", Presidio "San Salvatore" di Pesaro, Italy.
World J Oncol. 2012 Feb;3(1):39-41. doi: 10.4021/wjon441w. Epub 2012 Feb 19.
In this case report we describe the case of a patient with multiple bone metastases of NSCLC, adenocarcinoma with exon 21 point-mutation of EGFR, treated with gefitinib. After only 3 months, FDG-PET/CT scan showed a complete response of bone metastases and right hylar adenopathy. Implications for need of early use of FDG-PET/CT scan after gefitinib treatment are discussed.
在本病例报告中,我们描述了一名非小细胞肺癌(NSCLC)多发骨转移患者的病例,该患者为腺癌,伴有表皮生长因子受体(EGFR)第21外显子点突变,接受了吉非替尼治疗。仅3个月后,氟代脱氧葡萄糖正电子发射断层显像/X线计算机体层成像(FDG-PET/CT)扫描显示骨转移和右肺门淋巴结病完全缓解。本文讨论了吉非替尼治疗后早期使用FDG-PET/CT扫描的必要性。