Shirzadi Ali, Drazin Doniel, Shirzadi Neda, Westhout Franklin, Drazin Noam, Fan Xuemo, Acosta Frank L
Department of Neurosurgery, Cedars Sinai Medical Center, Los Angeles, CA, USA.
Department of Internal Medicine, Division of Hematology/Oncology, Cedars Sinai Medical Center, Los Angeles, CA, USA.
World J Oncol. 2012 Aug;3(4):182-186. doi: 10.4021/wjon481w. Epub 2012 Aug 26.
Uterine leiomyosarcomas do not frequently metastasize to the bone, and spinal column metastases are even less common. Surgery is the treatment of choice. Adjuvant radiation with or without chemotherapy depending on the extent of disease can be beneficial. We present the case of leiomyosarcoma metastasis to the spine with a previous history of known primary disease complicated by thrombocytopenia. Thrombocytopenia can present surgical challenges, but can also be present concurrently unrelated to the primary disease. A thorough evaluation is needed to rule out any underlying lymphoproliferative disorder or microangiopathic phenomenon.
子宫平滑肌肉瘤很少转移至骨骼，脊柱转移更为罕见。手术是首选治疗方法。根据疾病范围，辅助放疗加或不加化疗可能有益。我们报告一例既往有已知原发性疾病病史且并发血小板减少症的平滑肌肉瘤脊柱转移病例。血小板减少症会带来手术挑战，但也可能与原发性疾病无关而同时存在。需要进行全面评估以排除任何潜在的淋巴增殖性疾病或微血管病变现象。
