Chiang Kuo-Hwa, Hung Shun-Hsing, Chang Sheng-Tsung
Division of Chest Medicine, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Department of Information Management, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
World J Oncol. 2013 Apr;4(2):118-121. doi: 10.4021/wjon630w. Epub 2013 May 6.
Pulmonary metastases are not encountered commonly in patients with prostate cancer. Pulmonary metastases with pneumothorax as a presenting clinical manifestation in newly diagnosed prostate cancer are very rare. Here, we present the case of an 82-year-old patient who was admitted to our center with a chief complaint of worsening dyspnea over the past few days. The chest X-ray and computed tomography (CT) showed left pneumothorax and bilateral lung opacities as well as generalized lymphadenopathy and diffuse bony metastases. After a series of workup including cervical lymph node biopsy with immunohistochemical staining, abdomen CT, serum prostate-specific antigen (PSA), and transrectal ultrasonography (TRUS), he was proved to have prostate cancer with multiple lung, bone and lymph node metastases. This case is reported because of the rarity for a prostate carcinoma presented clinically with an unusual pulmonary manifestation.
前列腺癌患者中肺转移并不常见。以气胸作为新诊断前列腺癌的首发临床表现的肺转移非常罕见。在此，我们报告一例82岁患者，因过去几天呼吸困难加重为主诉入住我院。胸部X线和计算机断层扫描（CT）显示左侧气胸、双侧肺混浊以及全身淋巴结肿大和弥漫性骨转移。经过一系列检查，包括颈部淋巴结活检及免疫组化染色、腹部CT、血清前列腺特异性抗原（PSA）和经直肠超声检查（TRUS），证实他患有前列腺癌伴多发肺、骨和淋巴结转移。报告该病例是因为前列腺癌临床上表现为不寻常肺部表现的情况很罕见。
