培美曲塞诱导的间质性肺炎：一例病例研究及文献综述

Pemetrexed-Induced Interstitial Pneumonitis: A Case Study and Literature Review.

作者信息

Waters Michael J, Sukumaran Shawgi, Karapetis Chris S

机构信息

Royal Adelaide Hospital, Adelaide, South Australia 5000, Australia.

Department of Medical Oncology, Flinders Medical Centre, Bedford Park, Adelaide, South Australia 5042, Australia.

出版信息

World J Oncol. 2014 Dec;5(5-6):232-236. doi: 10.14740/wjon845w. Epub 2014 Dec 3.

DOI:10.14740/wjon845w

PMID:29147410

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649774/

Abstract

Pemetrexed is a new-generation antifolate drug, now widely used in patients with non-small cell lung cancer (NSCLC). We report a case of pemetrexed-induced interstitial pneumonitis, and review the literature of eight previously reported cases. As pemetrexed is now a widely used chemotherapeutic agent, it is important to be aware of rare adverse events related to its administration.

摘要

培美曲塞是一种新一代抗叶酸药物，目前广泛应用于非小细胞肺癌（NSCLC）患者。我们报告了一例培美曲塞诱发的间质性肺炎病例，并回顾了先前报道的8例病例的文献。由于培美曲塞目前是一种广泛使用的化疗药物，了解与其使用相关的罕见不良事件很重要。