1Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; and.
2Department of Orthopaedic Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
J Neurosurg Spine. 2018 Feb;28(2):131-139. doi: 10.3171/2017.5.SPINE161211. Epub 2017 Nov 17.
OBJECTIVE This study aimed to compare the clinical results of using posterior fixation and fusion with or without anterior decompression to treat os odontoideum with atlantoaxial dislocation. METHODS Twenty-five consecutive patients with os odontoideum were included in this study. Sixteen patients with reducible atlantoaxial dislocation were treated by single-level posterior fusion and stabilization; the other 9 were treated with posterior fusion and stabilization combined with transoral decompression. Pre- and postoperative CT scans and MR images were obtained. RESULTS Twenty-four patients were followed for 24-54 months (average 36.5 months). Postoperative CT scans indicated that all pedicle screws were placed satisfactorily except in 2 cases, in which the screws slightly penetrated the transverse foramen. Postoperative MR images demonstrated that sufficient decompression of the spinal cord was obtained in all patients. Complications included 1 case each of pedicle screw breakage, pharynx ulcer, and persistent pharynx discomfort. Statistical analysis of all cases revealed that mean Japanese Orthopaedic Association scores improved from a preoperative score of 10.2 (range 7-13) to a postoperative score of 15.6 (range 11-18). CONCLUSIONS Patients who have os odontoideum with a reducible atlantoaxial dislocation can be effectively treated with single-level posterior fusion and stabilization. Combined transoral decompression and posterior fusion and stabilization is recommended for those with irreducible atlantoaxial dislocation.
比较后路固定融合术联合或不联合前路减压治疗寰枢椎脱位齿状突骨不连的临床效果。
回顾性分析 25 例齿状突骨不连伴寰枢椎脱位患者的临床资料。16 例可复性寰枢椎脱位患者行单节段后路融合固定,9 例不可复性寰枢椎脱位患者行后路融合固定联合经口前路减压。术前及术后均行 CT 及 MRI 检查。
24 例患者获得随访,随访时间 2454 个月,平均 36.5 个月。术后 CT 扫描显示除 2 例螺钉轻微穿透横突孔外,其余所有椎弓根螺钉均位置满意。术后 MRI 显示脊髓减压充分。术后并发症包括椎弓根螺钉断裂 1 例、咽溃疡 1 例、咽不适感持续存在 1 例。所有患者的日本矫形外科学会(JOA)评分由术前的 10.2 分(713 分)提高至术后的 15.6 分(11~18 分)。
对于可复性寰枢椎脱位的患者,行单节段后路融合固定可获得良好的疗效;对于不可复性寰枢椎脱位的患者,建议行后路融合固定联合经口前路减压。