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同卵双胞胎中的寰枢椎脱位与齿突小骨:病因学观点

Atlantoaxial dislocation and os odontoideum in two identical twins: perspectives on etiology.

作者信息

Tang Xiangsheng, Tan Mingsheng, Yi Ping, Yang Feng, Hao Qingying

机构信息

Department of Spinal Surgery, China-Japan Friendship Hospital, Beijing, 100029, China.

出版信息

Eur Spine J. 2018 Jul;27(Suppl 3):259-263. doi: 10.1007/s00586-017-5116-5. Epub 2017 May 15.

DOI:10.1007/s00586-017-5116-5
PMID:28508240
Abstract

PURPOSE

There are two theories about the origin of os odontoideum: traumatic or congenital. However, most studies favor the hypothesis of traumatic theory. To emphasize the congenital theory, we report a pair of identical twins both with atlantoaxial dislocation and os odontoideum, which is believed to be a congenital defect.

METHODS

We present two 14-year-old identical twins with atlantoaxial dislocation and os odontoideum. Neither of the twins had history of trauma in head nor cervical spine. We reviewed and compared the cervical radiographs of the identical twins. Posterior atlantoaxial reduction, pedicle screw fixation and atlantoaxial fusion were performed for the two twins.

RESULTS

Radiological examination showed the identical twins had typical atlantoaxial dislocation and os odontoideum. The twins had high similarity in the appearance of atlantoaxial dislocation and os odontoideum. The etiology of the os odontoideum in the twins is believed to be congenital. Both the twins had improvement in neurological function after surgery.

CONCLUSION

Although a great number of cases with os odontoideum have been reported to be traumatic, there are some cases believed to be congenital.

摘要

目的

关于齿突骨的起源有两种理论:创伤性或先天性。然而,大多数研究支持创伤理论假说。为强调先天性理论,我们报告一对同卵双胞胎均患有寰枢椎脱位和齿突骨,后者被认为是一种先天性缺陷。

方法

我们呈现了两名患有寰枢椎脱位和齿突骨的14岁同卵双胞胎。这对双胞胎均无头部或颈椎创伤史。我们回顾并比较了这对同卵双胞胎的颈椎X线片。对这两名双胞胎进行了寰枢椎后路复位、椎弓根螺钉固定及寰枢椎融合术。

结果

影像学检查显示这对同卵双胞胎患有典型的寰枢椎脱位和齿突骨。这对双胞胎在寰枢椎脱位和齿突骨的表现上具有高度相似性。双胞胎中齿突骨的病因被认为是先天性的。两名双胞胎术后神经功能均有改善。

结论

尽管大量齿突骨病例据报道为创伤性的,但仍有一些病例被认为是先天性的。

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