Beamer Laura C.
Northern Illinois University.
Clin J Oncol Nurs. 2017 Dec 1;21(6):730-737. doi: 10.1188/17.CJON.730-737.
The field of genetics and genomics is rapidly expanding, particularly in oncology. Genetics and genomics can lead to ethical concerns. Oncology nurses must balance the need for evidence-based oncology care with that of ethical care for patients and their family members.
The purpose of this article is to provide an overview of cancer genetics and ethics and their impact on oncology nurses, patients, and families.
METHODS: A case study of familial adenomatous polyposis (FAP) is offered to illustrate the impact of a hereditary cancer syndrome on several generations of a family and ethical issues surrounding cancer genetics. In addition, a brief review of FAP, gene and tissue biobanking, and genome editing is provided. .
Genetics, genomics, and pharmaco-genomics are ubiquitous in cancer diagnosis and management. Nurses must be knowledgeable about the ethical issues related to cancer genetics and oncology care to advocate for the needs of patients with cancer. Communication with and education of patients and their families before germline genetic testing may reduce the emergence of ethical dilemmas.
遗传学和基因组学领域正在迅速扩展，尤其是在肿瘤学领域。遗传学和基因组学可能引发伦理问题。肿瘤学护士必须在基于证据的肿瘤护理需求与为患者及其家属提供伦理护理的需求之间取得平衡。
本文旨在概述癌症遗传学与伦理及其对肿瘤学护士、患者和家庭的影响。
提供一个家族性腺瘤性息肉病（FAP）的案例研究，以说明遗传性癌症综合征对一个家庭几代人的影响以及围绕癌症遗传学的伦理问题。此外，还对FAP、基因和组织生物样本库以及基因组编辑进行了简要综述。
遗传学、基因组学和药物基因组学在癌症诊断和管理中无处不在。护士必须了解与癌症遗传学和肿瘤护理相关的伦理问题，以便为癌症患者的需求进行倡导。在进行种系基因检测之前与患者及其家属进行沟通和教育，可能会减少伦理困境的出现。
