Messerli Michael, Hechelhammer Lukas, Leschka Sebastian, Warschkow René, Wildermuth Simon, Bauer Ralf W
Division of Radiology and Nuclear Medicine, Cantonal Hospital St. Gallen, Switzerland; Department of Nuclear Medicine, University Hospital Zurich, University Zurich, Switzerland.
Division of Radiology and Nuclear Medicine, Cantonal Hospital St. Gallen, Switzerland.
Clin Imaging. 2018 May-Jun;49:73-79. doi: 10.1016/j.clinimag.2017.10.014. Epub 2017 Oct 25.
To determine the value of ultra-low dose chest CT with tin filtration for ordinal coronary artery calcium (CAC) risk scoring.
50 patients were prospectively included and underwent clinical standard dose chest CT (1.8±0.7mSv) and ultra-low dose CT (0.13±0.01mSv). Four radiologists estimated presence and extent of CAC.
Weighted kappa values for CAC were 0.76-0.97 in standard dose and 0.75-0.95 in ultra-low dose CT (p<0.001). Good to excellent agreement was observed for CAC ordinal risk assessment, with readers reporting identical risk in 81% of cases.
CAC risk can be qualitatively assessed from X-ray dose equivalent ungated chest CT.
确定采用锡过滤的超低剂量胸部CT用于冠状动脉钙化（CAC）序数风险评分的价值。
前瞻性纳入50例患者，他们接受了临床标准剂量胸部CT（1.8±0.7mSv）和超低剂量CT（0.13±0.01mSv）检查。四名放射科医生评估了CAC的存在情况和范围。
标准剂量下CAC的加权kappa值为0.76 - 0.97，超低剂量CT下为0.75 - 0.95（p<0.001）。对于CAC序数风险评估，观察到良好至优秀的一致性，读者在81%的病例中报告了相同的风险。
可以从X射线剂量等效的非门控胸部CT定性评估CAC风险。
