Tretbar L L
University of Missouri, Kansas City, School of Medicine.
J Dermatol Surg Oncol. 1989 Feb;15(2):223-5. doi: 10.1111/j.1524-4725.1989.tb03029.x.
A 20-year experience using sodium tetradecyl sulfate (Sotradecol, Elkins-Sinn, Inc., Cherry Hill, NJ) for the injection treatment of spider telangiectasias is reviewed. Of 1426 legs injected, 882 were treated with a 1%-solution injected directly into the spider veins, and 264 were injected directly with a 1/3%-solution. With the 1/3%-solution, the remaining 280 legs had the blue veins feeding the spider telangiectasias injected rather than the spider itself. When injected directly into the spider veins, the lesser concentration gave fewer ulcerations and less pigmentation, but equal treatment results. Injecting the subcutaneous feeder veins appears to provide more permanent clearing of the lesions with fewer recurrences and no side effects. No allergic or other major complications occurred with the injection treatments.
回顾了使用十四烷基硫酸钠(Sotradecol,Elkins-Sinn公司,新泽西州樱桃山)注射治疗蜘蛛状毛细血管扩张症20年的经验。在注射的1426条腿中,882条用1%溶液直接注射到蜘蛛状静脉中,264条直接用1/3%溶液注射。对于1/3%溶液,其余280条腿注射的是为蜘蛛状毛细血管扩张症供血的蓝色静脉,而不是蜘蛛状静脉本身。直接注射到蜘蛛状静脉中时,较低浓度导致的溃疡和色素沉着较少,但治疗效果相同。注射皮下供血静脉似乎能更持久地清除病变,复发较少且无副作用。注射治疗未出现过敏或其他重大并发症。