毛细血管扩张症的治疗：硬化剂比较
Treatment of telangiectasia: comparison of sclerosing agents.
作者信息
Carlin M C, Ratz J L
机构信息
Department of Dermatology, Cleveland Clinic Foundation, Ohio.
出版信息
J Dermatol Surg Oncol. 1987 Nov;13(11):1181-4. doi: 10.1111/j.1524-4725.1987.tb02429.x.
A double-blind, double-paired comparison, placebo-controlled study was undertaken to determine the optimal agent for sclerotherapy of spider telangiectasias of the lower extremities. Sodium tetradecyl sulfate 0.5%, polidocanol 0.25%, heparsal, and normal saline control were evaluated in terms of clinical effectiveness and patient acceptance. Although all of the agents, except for the control, were effective, polidocanol was found to have the fewest adverse reactions and afforded the greatest patient comfort.
开展了一项双盲、双配对比较、安慰剂对照研究，以确定下肢蜘蛛状毛细血管扩张症硬化治疗的最佳药物。对0.5%的十四烷基硫酸钠、0.25%的聚多卡醇、肝磷脂和生理盐水对照在临床疗效和患者接受度方面进行了评估。尽管除对照外的所有药物均有效，但发现聚多卡醇的不良反应最少，且能为患者带来最大程度的舒适感。
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