de Jager Edwin John, Du Plessis André Francois, Hoffman Jakobus Willem, Oettlé Anna Catherina, Bosman Marius Casparus
Department of Anatomy, Faculty of Health Science, University of Pretoria, South Africa.
Department of Education Innovation, University of Pretoria, South Africa.
Anat Rec (Hoboken). 2018 Jul;301(7):1138-1147. doi: 10.1002/ar.23726. Epub 2017 Dec 1.
Conceptualization of the ventricular system of the brain by macroscopic studies is complicated by the lack of physical structure of these interconnected cavities. Dissection procedures designed to display the structures in the walls of the ventricles are destructive and not conducive for the appreciation of the ventricular system in its entirety. The application of Micro-focus X-ray tomography affords the possibility to appreciate hidden structures in a nondestructive manner. The aim of this study was to explore the possibility of using micro-focus X-ray tomography in the three-dimensional (3D) visualization of the ventricular system as well as the various neuroanatomical structures within its walls for educational purposes. Randomly selected embalmed human cadaver brains were scanned at Necsa (South African Nuclear Energy Corporation) housing the MIXRAD laboratory consisting of a Nikon XTH 225 ST micro-focus X-ray tomography facility. A 3D flythrough video of the ventricular system was reconstructed from these scans using software to view the inner surface of the ventricles. Micro-focus X-ray tomography provides feasible means of delivering high-resolution images in a nondestructive way to design a representation of the ventricular system. In addition, structures in the walls of the ventricular system could be appreciated in a novel way. It is envisaged that this 3D-fly-through video of the ventricular system will be valuable when integrated with standard prosections and atlas pictures in the educational setting. Further studies evaluating the use of this integrative visualization of the ventricular system of the brain for its applicability in the educational setting should be performed. Anat Rec, 301:1138-1147, 2018. © 2017 Wiley Periodicals, Inc.
通过宏观研究对脑室内系统进行概念化存在困难，因为这些相互连接的腔室缺乏实体结构。旨在展示脑室壁结构的解剖程序具有破坏性，不利于整体观察脑室系统。微焦点X射线断层扫描技术的应用为无损观察隐藏结构提供了可能。本研究的目的是探索使用微焦点X射线断层扫描技术对脑室系统及其壁内各种神经解剖结构进行三维（3D）可视化，以用于教学目的。随机选取经过防腐处理的人类尸体大脑，在南非核能公司（Necsa）的MIXRAD实验室进行扫描，该实验室配备尼康XTH 225 ST微焦点X射线断层扫描设备。利用软件从这些扫描图像中重建出脑室系统的3D穿梭视频，以观察脑室的内表面。微焦点X射线断层扫描技术提供了一种可行的方法，能够以无损方式提供高分辨率图像，从而构建脑室系统的模型。此外，还可以以一种新颖的方式观察脑室壁内的结构。预计将这种脑室系统的3D穿梭视频与教学环境中的标准断层解剖图和图谱图片相结合时，将具有重要价值。应进一步开展研究，评估这种脑室内系统综合可视化技术在教学环境中的适用性。《解剖学记录》，301:1138 - 1147，2018年。© 2017威利期刊公司。
