Risher W H, Crocker E F, Beckman E N, Blalock J B, Ochsner J L
Department of Surgery, Oshsner Clinic, New Orleans, LA 70121.
J Thorac Cardiovasc Surg. 1989 Feb;97(2):303-8.
Pulmonary dirofilariasis caused by Dirofilaria immitis, the dog heartworm, is a rarely reported pulmonary lesion. It appears as a solitary pulmonary nodule, and the diagnosis is not established until thoracotomy and subsequent histologic examination of the specimen are performed. Sporadic reports of pulmonary dirofilariasis in the United States total only 70 cases. The six resections of pulmonary dirofilariasis at the Ochsner Clinic represent the largest reported series of cases originating at a single institution. We present an overview of the pathogenesis of this disease, its clinical manifestations, pathologic and epidemiologic features, and geographic distribution. The prevalence of pulmonary dirofilariasis appears to be increasing; hence, thoracic surgeons and pathologists need to be alert to this cause of granulomatous pulmonary lesions.
由犬心丝虫（恶丝虫）引起的肺恶丝虫病是一种鲜有报道的肺部病变。它表现为单个肺结节，直到进行开胸手术并对标本进行后续组织学检查才能确诊。美国关于肺恶丝虫病的零星报道总共只有70例。奥施纳诊所对6例肺恶丝虫病进行的切除手术是来自单一机构的最大病例报道系列。我们概述了这种疾病的发病机制、临床表现、病理和流行病学特征以及地理分布。肺恶丝虫病的患病率似乎在上升；因此，胸外科医生和病理学家需要警惕这种肉芽肿性肺部病变的病因。
