Krengli M, Gambaro G, Pisani P, Pastore G
Ospedale Maggiore, Novara.
Minerva Med. 1989 Jan;80(1):35-41.
Radiotherapy obtains better results when employed alone, in initial forms (T1-T2), and after surgery, when loco-regional relapse incidence reduces. Personal results in the treatment of laryngeal cancer are reported in 281 patients. One-hundred-forty-seven patients treated with exclusive radiotherapy had 5-year global and NED survival of 32.7% and 26.6%; 5-year NED survival in particular was 78.7% for T1-T2 and 22.9% for T3-T4. Subsequently 52.8% of patients relapsed. One-hundred-thirty-four patients treated with postoperative radiotherapy had a 5-year global and NED survival of 58.8% and 52.1%; relapses were observed in 20.9% of patients, mostly in cases with histological G3 grading or with rupture of the lymph node capsule. The importance of exclusive and postoperative radiotherapy with reference to prognostic factors that are deduced from the histological specimen is underlined.
单独使用放疗、在疾病初期（T1 - T2期）以及术后使用放疗时，当局部区域复发率降低，放疗可取得更好的效果。本文报告了281例喉癌患者的个人治疗结果。147例仅接受放疗的患者5年总体生存率和无疾病证据生存率分别为32.7%和26.6%；T1 - T2期患者5年无疾病证据生存率尤其为78.7%，T3 - T4期为22.9%。随后，52.8%的患者复发。134例接受术后放疗的患者5年总体生存率和无疾病证据生存率分别为58.8%和52.1%；20.9%的患者出现复发，主要是组织学分级为G3或淋巴结包膜破裂的病例。强调了单纯放疗和术后放疗对于从组织学标本推断出的预后因素的重要性。
