Franchini Massimo, Mannucci Pier Mannuccio
Department of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantua, Italy.
Scientific Direction, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, University of Milan, Via Pace 9, Milan, Italy.
Drugs Aging. 2017 Dec;34(12):881-889. doi: 10.1007/s40266-017-0500-8.
In recent decades, several improvements in hemophilia care have resulted in increased quality of life and life expectancy for those affected by this inherited hemorrhagic condition. Nowadays, individuals with hemophilia enjoy a life expectancy at birth close to that of males in the general population. As a consequence of the increasing age of the hemophilia population, a growing number of these patients develop age-related co-morbidities, such as cardiovascular disease and cancer, the management of which represents a new challenge for caregivers at hemophilia treatment centers. This narrative review focuses on the clinical problems arising in older people with hemophilia, with particular attention to the optimal therapeutic strategies.
近几十年来,血友病护理方面的多项改进提高了受这种遗传性出血性疾病影响者的生活质量和预期寿命。如今,血友病患者出生时的预期寿命接近普通人群中的男性。由于血友病患者群体的年龄不断增加,越来越多的这些患者出现与年龄相关的合并症,如心血管疾病和癌症,对这些合并症的管理给血友病治疗中心的护理人员带来了新的挑战。本叙述性综述重点关注老年血友病患者出现的临床问题,尤其关注最佳治疗策略。