Weller R E, Pool R R, Hornof W J
J Am Vet Med Assoc. 1979 Jul 1;175(1):56-60.
A 9-year-old male German Shepherd Dog with osteogenic sarcoma involving the right humerus was treated by scapulohumeral disarticulation and adjuvant chemotherapy. Doxorubicin was used, at a dosage of 30 mg/m2 of body surface. Chemotherapy was unsuccessful, and 4 months after surgery, the dog developed multiple metastases of osteogenic sarcoma in the appendicular skeleton, a metastatic pattern rarely observed with primary bone tumors.
一只9岁的雄性德国牧羊犬,患有累及右肱骨的骨肉瘤,接受了肩胛肱骨离断术和辅助化疗。使用了阿霉素,剂量为30毫克/平方米体表面积。化疗未成功,术后4个月,该犬在四肢骨骼出现了骨肉瘤的多处转移,这种转移模式在原发性骨肿瘤中很少见。