1 Clinical Trial Unit, Swiss Paraplegic Center , Nottwil, Switzerland .
2 Swiss Paraplegic Research (SPF), ICF Unit , Nottwil, Switzerland .
J Neurotrauma. 2018 Mar 15;35(6):854-863. doi: 10.1089/neu.2017.5195. Epub 2018 Jan 16.
The Graded and Redefined Assessment of Strength, Sensibility and Prehension (GRASSP) is a valid, reliable, and responsive outcome measure to evaluate upper limb function in individuals with tetraplegia. GRASSP generates ordinal total scores; therefore, applicability as an interval level measurement requires testing of its measurement properties. This study examined the metric characteristics with Rasch Analysis to derive interval level scales of the respective GRASSP subtests. The GRASSP was recorded within 10 days, and at 1, 3, 6, and 12 months after cervical spinal cord injury (SCI). Rasch analysis was performed for each GRASSP subscale to assess the following metric assumptions: absence of local item dependency (LID), unidimensionality, monotonicity, item and model fit, reliability, and absence of differential item functioning (DIF) for side (left and right) and examination stage. If these assumptions could not be met, adjustments were undertaken to achieve a good fit to the Rasch model. Seventy-seven individuals with cervical SCI were included (n = 154 arms). Stacking the data for the side (left and right) resulted in a total of 614 observations, which were based on the repeated measurements. With minor adjustments, the GRASSP subscales showed good reliability, item fit, and ordered response options. Local item dependencies were found in the strength and sensibility subscales. Redundancies among some measurement items allowed shortening of the subscales without reasonable loss of reliability. Absence of DIF for the examination stage supported robustness of the subscales over time. The modified GRASSP, now Version 2, subtest scores can be applied as interval level measurements, and the reduction of items within subscales allows for shorter assessment times in clinical studies without degrading metric properties.
分级和重新定义的上肢力量、感觉和抓握评估(GRASSP)是一种有效的、可靠的、灵敏的上肢功能评估方法,适用于四肢瘫痪患者。GRASSP 生成有序的总分;因此,作为区间水平测量,需要测试其测量特性。本研究使用 Rasch 分析来检验其度量特性,以获得各自 GRASSP 子测试的区间水平量表。GRASSP 在颈椎脊髓损伤(SCI)后 10 天内以及 1、3、6 和 12 个月内进行记录。Rasch 分析用于每个 GRASSP 子量表,以评估以下度量假设:不存在局部项目依赖性(LID)、单维性、单调性、项目和模型拟合、可靠性以及左右侧和检查阶段的项目功能差异(DIF)。如果不能满足这些假设,则进行调整以实现与 Rasch 模型的良好拟合。共纳入 77 例颈椎 SCI 患者(n=154 侧)。对侧(左和右)的数据进行堆叠,总共获得 614 次重复测量的观察值。经过轻微调整,GRASSP 子量表显示出良好的可靠性、项目拟合和有序反应选项。在力量和感觉子量表中发现了局部项目依赖性。一些测量项目之间的冗余允许缩短子量表,而不会合理地损失可靠性。检查阶段的 DIF 缺失支持了子量表随时间的稳健性。经过修改的 GRASSP 现在的版本 2 子测试分数可以作为区间水平测量应用,并且子量表内项目的减少可以在不降低度量特性的情况下缩短临床研究中的评估时间。