Testicular feminization syndrome: a case study of four generations.

This report deals with the complete form of testicular feminization in four generations of a single kindred. The four siblings who have had orchiectomy had no evidence of testicular malignancy. Because all four of the postpubertal patients have the complete form of the disorder, the prepubertal member is being managed expectantly, awaiting the onset of female secondary sexual characteristics at puberty. Other carriers may be identified as reproductive function continues.