Bakke J V
Tidsskr Nor Laegeforen. 1989 Jan 30;109(3):341-4.
Large variations in the development of chronic airway disturbances in the population have been uncovered, together with possible increased risk of such disturbances. There seems to be a connection to exposure to pollutants at work and in home environment. The interconnection and interaction between irritants, allergens, infectious agents and other biologically active substances may have a decisive impact on the risk an individual runs of developing chronic suffering in the upper and lower respiratory tract. Injuries in mucous membranes and airways, connected with the development of unspecific hyperreactivity may play a central role in the development of allergic and nonallergic airway disturbances and diseases. These findings may have a decisive influence on the choice of prophylaxis and therapy.
人们发现人群中慢性气道疾病的发展存在很大差异,且此类疾病的风险可能增加。这似乎与工作场所和家庭环境中接触污染物有关。刺激物、过敏原、传染因子和其他生物活性物质之间的相互联系和相互作用,可能对个体患上下呼吸道慢性疾病的风险产生决定性影响。与非特异性高反应性发展相关的黏膜和气道损伤,可能在过敏性和非过敏性气道疾病的发展中起核心作用。这些发现可能对预防和治疗方法的选择产生决定性影响。