Arslan Harun, Yavuz Alpaslan, Arslan Ayşe, Aycan Abdurrahman
Department of Radiology, Van Yuzuncu Yıl University, Dursun Odabası Faculty of Medicine, Van, Turkey.
Department of Nutrition, Faculty of Health Science, Van Yuzuncu Yıl University, Van, Turkey.
Neurol Neurochir Pol. 2018 Jan-Feb;52(1):107-111. doi: 10.1016/j.pjnns.2017.11.006. Epub 2017 Nov 14.
IgA vasculitis (IgAV) is a leukocytoclastic vasculitis and characterized by involvement of small vessels in skin, gastrointestinal system, joints, kidneys, and less frequently other organs. It is the commonest vasculitis in childhood and etiology is not completely known. Neurological manifestations of IgAV are very rare and usually seen in patients with severe hypertension or as an uncommon feature such as peripheral neuropathy. Posterior reversible encephalopathy syndrome (PRES) is a clinic-radiologic entity characterized with temporary vasogenic edema developing typically in posterior circulation of the brain and has been reported as a rare manifestation of IgAV. In this paper, a PRES case of 14-year-old male with IgAV is reported and etiopathogenesis was discussed with literature. Diagnosis was made by magnetic resonance imaging because of the existence of neurological symptoms (headache and visual loss) during the course of disease. His radiological findings have resolved with therapy. Although neurological involvement is a rare manifestation in IgAV, we recommend magnetic resonance imaging in such patients for diagnosis and evaluation of complications.
IgA 血管炎（IgAV）是一种白细胞破碎性血管炎，其特征是皮肤、胃肠道系统、关节、肾脏等小血管受累，其他器官受累较少见。它是儿童时期最常见的血管炎，病因尚不完全清楚。IgAV 的神经表现非常罕见，通常见于严重高血压患者或作为外周神经病变等不常见特征出现。后部可逆性脑病综合征（PRES）是一种临床-影像学实体，其特征是通常在脑后部循环中出现暂时性血管源性水肿，已被报道为 IgAV 的罕见表现。本文报告了 1 例 14 岁男性 IgAV 合并 PRES 的病例，并结合文献对其病因发病机制进行了讨论。由于疾病过程中存在神经症状（头痛和视力丧失），通过磁共振成像做出诊断。其影像学表现经治疗后已消退。虽然神经受累在 IgAV 中是罕见表现，但我们建议对这类患者进行磁共振成像检查以诊断和评估并发症。
