四种从菘蓝根茎中提取的新糖苷。

Four New Glycosides from the Rhizoma of Anemarrhena asphodeloides.

机构信息

Key Laboratory of Chinese Materia Medica, Ministry of Education of Heilongjiang University of Chinese Medicine, Harbin 150040, China.

Heilongjiang Institute for Food and Drug Control, Harbin 150001, China.

出版信息

Molecules. 2017 Nov 22;22(11):1995. doi: 10.3390/molecules22111995.

DOI:10.3390/molecules22111995

PMID:29165329

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6150167/

Abstract

Four new compounds, aneglycoside A-C (-) and timosaponin U (), were isolated from the rhizomes of . Their structures were determined through extensive spectroscopic analysis, chemical characteristics, and high-resolution mass spectrometry (HRMS). All the isolations were evaluated for cytotoxicity against HepG2, Hela, and SGC7901 human cancer lines. Compounds , , and showed weak antiproliferative activities on HepG2, Hela, and SGC7901 cells.

摘要

从的根茎中分离得到了四个新化合物，分别为 aneglycoside A-C (-) 和 timosaponin U ()。通过广泛的光谱分析、化学特性和高分辨率质谱 (HRMS) 确定了它们的结构。对所有分离物进行了抗 HepG2、Hela 和 SGC7901 人癌细胞系的细胞毒性评价。化合物、和对 HepG2、Hela 和 SGC7901 细胞表现出较弱的增殖抑制活性。