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68Ga-前列腺特异性膜抗原摄取在胃肠道间质瘤中的应用。

68Ga-Prostate-Specific Membrane Antigen Uptake in Gastrointestinal Stromal Tumor.

出版信息

Clin Nucl Med. 2018 Jan;43(1):60-61. doi: 10.1097/RLU.0000000000001902.

DOI:10.1097/RLU.0000000000001902
PMID:29166327
Abstract

A 62-year-old man with recently diagnosed prostatic adenocarcinoma was referred for a whole-body Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for staging. Although the scan did not reveal metastatic disease, it did reveal a PSMA-avid lesion in the upper abdomen located between the liver and the stomach. Histopathologic examination demonstrated a gastrointestinal stromal tumor. The lesion demonstrated increased uptake in the margins of the tumor with a central photopenic area, which we consider to be the typical pattern on PSMA images of a gastrointestinal stromal tumor, based on theoretical PSMA distribution in such a tumor and other reported cases.

摘要

一位 62 岁男性,近期诊断为前列腺腺癌,为进行分期进行全身 Ga-前列腺特异性膜抗原(PSMA)PET/CT 扫描。虽然扫描未发现转移病灶,但确实在肝脏和胃之间的上腹部发现一个 PSMA 阳性病灶。组织病理学检查显示胃肠道间质瘤。病变在肿瘤边缘摄取增加,中央出现透光区,我们认为这是胃肠道间质瘤 PSMA 图像的典型模式,基于该肿瘤中 PSMA 的理论分布和其他报道的病例。

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J Clin Med. 2022 Nov 7;11(21):6590. doi: 10.3390/jcm11216590.
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