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[急性、亚急性和慢性背痛住院保守治疗的评估]

[Evaluation of Inpatient Conservative Management of Acute, Subacute, and Chronic Back Pain].

作者信息

Haase Ingo, Haase Kilian, Kladny Bernd

机构信息

Forschung, Entwicklung, Qualitätssicherung, m&i-Klinikgruppe Enzensberg, Hopfen am See.

Abteilung Orthopädie und Unfallchirurgie, m&i-Fachklinik Herzogenaurach.

出版信息

Z Orthop Unfall. 2018 Apr;156(2):184-192. doi: 10.1055/s-0043-120201. Epub 2017 Nov 22.

Abstract

BACKGROUND

Backache is very common in the German population. It is a common reason for people to seek medical advice and specific back pain programs have been developed. The intention of this study is to evaluate the short and long term effects of conservative management of back pain in a German general hospital. Outcomes of interest were pain intensity, interference in daily functions, physical functioning and health related quality of life.

PATIENTS AND METHODS

We examined 1010 patients with acute, subacute and chronic back pain, admitted to inpatient nonsurgical interventional therapy in a German hospital between July 2013 and July 2015. Outcomes were assessed at the end of the inpatient treatment and at 3, 6 and 12 months follow-up, using Numerical Rating Scales (NRS) for pain and daily function, the Hannover Ability Questionnaire for Measuring Back Pain-Related Functional Limitations (FFbH - R) and the German Version of the EuroQol Questionnaire (EQ-5D) for measuring health-related quality of life. The baseline questionnaire also included questions on the risk of developing long-term disability following back pain (HKF-R 10) for acute and subacute cases and the Mainz Pain Staging System (MPSS) for patients with chronic back pain. The return rate was 54% after 3 months, 38% after 6 months and 27% at 12 months follow-up. The results from the follow-up measurements (T2 - T5) were compared to the pre-treatment results (T1). Because of missing or insufficiently normal distributions nonparametric paired Wilcoxon tests were used to test differences over time for each variable. Level of significance was adjusted for multiple testing. In addition, effect sizes were computed to estimate the clinical relevance of statistically significant results.

RESULTS

Pain intensity and impact of pain on daily function were significantly lower at the end of the inpatient treatment (T2). The results remained largely stable at the 3, 6 and 12 month follow-ups. Significant improvements were found in physical functioning and health-related quality of life. These improvements were maintained equally at the 3, 6 and 12 month follow-ups. In consequence, working ability increased during the follow-up period. Calculated effect sizes showed large effects for pain intensity, interference and quality of life (r = 0.51 to 0.85) and predominately moderate effects (r = 0.45 to 0.62) for physical functioning at all measurement points. The percentage of patients who had an operation due to continuing back pain after conservative treatment was 7.8, 9.9, and 12.3 at the 3, 6, and 12 month follow-ups, respectively.

CONCLUSION

Persistent effects of inpatient conservative treatment of back pain were found for all outcome variables. The specific approach appears to be effective in conservative treatment programs of back pain. In the end, it's not about the alternative of surgery or conservative treatment for back pain. Treatment has to be coordinated with the patient in terms of participative decisions.

摘要

背景

背痛在德国人群中非常普遍。这是人们寻求医疗建议的常见原因,并且已经制定了特定的背痛治疗方案。本研究的目的是评估德国一家综合医院中背痛保守治疗的短期和长期效果。感兴趣的结果包括疼痛强度、对日常功能的干扰、身体功能以及与健康相关的生活质量。

患者与方法

我们对2013年7月至2015年7月期间在德国一家医院接受住院非手术介入治疗的1010例急性、亚急性和慢性背痛患者进行了检查。在住院治疗结束时以及随访3个月、6个月和12个月时,使用数字评分量表(NRS)评估疼痛和日常功能,使用汉诺威背痛相关功能受限测量能力问卷(FFbH -R)以及欧洲生活质量问卷德文版(EQ-5D)评估与健康相关的生活质量。基线问卷还包括针对急性和亚急性病例的背痛后发生长期残疾风险的问题(HKF-R 10)以及针对慢性背痛患者的美因茨疼痛分期系统(MPSS)。随访3个月后的回复率为54%,6个月后为38%,12个月后为27%。将随访测量结果(T2 - T5)与治疗前结果(T1)进行比较。由于分布缺失或分布不够正态,使用非参数配对威尔科克森检验来检验每个变量随时间的差异。显著性水平针对多重检验进行了调整。此外,计算效应量以估计具有统计学意义结果的临床相关性。

结果

住院治疗结束时(T2),疼痛强度以及疼痛对日常功能的影响显著降低。在3个月、6个月和12个月的随访中,结果基本保持稳定。身体功能和与健康相关的生活质量有显著改善。这些改善在3个月、6个月和12个月的随访中同样得以维持。因此;随访期间工作能力有所提高。计算出的效应量显示,在所有测量点,疼痛强度、干扰和生活质量方面的效应较大(r = 0.51至0.85),身体功能方面主要为中等效应(r = 0.45至0.62)。在3个月、6个月和12个月的随访中,因保守治疗后持续背痛而接受手术的患者百分比分别为7.8%、9.9%和12.3%。

结论

对于所有结果变量,均发现了住院保守治疗背痛的持续效果。这种特定方法在背痛保守治疗方案中似乎是有效的。最后,背痛治疗并非是手术或保守治疗的选择问题。治疗必须在参与性决策方面与患者进行协调。

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