新生儿全垂体功能减退继发胆汁淤积和高钙血症。

Cholestasis and hypercalcemia secondary to panhypopituitarism in a newborn.

作者信息

Dursun Fatma, Gerenli Nelgin, Kırmızıbekmez Heves

机构信息

Departments of Pediatric Endocrinology, Ümraniye Training and Research Hospital, İstanbul, Turkey.

Departments of Pediatric Gastroenterology, Ümraniye Training and Research Hospital, İstanbul, Turkey.

出版信息

Turk J Pediatr. 2017;59(1):100-103. doi: 10.24953/turkjped.2017.01.020.

DOI:10.24953/turkjped.2017.01.020

PMID:29168375

Abstract

Dursun F, Gerenli N, Kırmızıbekmez H. Cholestasis and hypercalcemia secondary to panhypopituitarism in a newborn. Turk J Pediatr 2017; 59: 100-103. Cholestatic hepatitis and hypercalcemia are rare features of hypopituitarism in newborns. So diagnosis of hypopituitarism is frequently delayed. The most frequent symptoms of congenital hypopituitarism are hypoglycemia, prolonged jaundince and micropenis. A patient with congenital hypopituitarism associated with cholestasis and hypercalcemia is reported here. Newborns with hypercalcemia and cholestasis should alert pediatricians to the possibility of congenital hypopituitarism and prompt endocrinological investigation.

摘要

杜尔孙·F、盖伦利·N、基尔米兹贝克梅兹·H。一名新生儿全垂体功能减退继发胆汁淤积和高钙血症。《土耳其儿科学杂志》2017年；59: 100 - 103。胆汁淤积性肝炎和高钙血症是新生儿垂体功能减退的罕见特征。因此，垂体功能减退的诊断常常延迟。先天性垂体功能减退最常见的症状是低血糖、黄疸持续时间延长和小阴茎。本文报告了一名患有先天性垂体功能减退并伴有胆汁淤积和高钙血症的患者。患有高钙血症和胆汁淤积的新生儿应提醒儿科医生注意先天性垂体功能减退的可能性，并及时进行内分泌学检查。