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先天性全垂体功能减退症中的低血糖和胆汁淤积性黄疸

[Hypoglycemia and cholestatic jaundice in congenital panhypopituitarism].

作者信息

Haagen M, Akkurt I, Blunck W

机构信息

Pädiatrische Abteilung, Altonaer Kinderkrankenhaus, Hamburg.

出版信息

Monatsschr Kinderheilkd. 1989 Oct;137(10):678-80.

PMID:2586535
Abstract

The case of a female newborn who was first found to have severe recurrent hypoglycemia and then developed cholestasis with conjugated hyperbilirubinemia is presented. No infectious diseases, metabolic defects, or disease of the hepatobiliary system were found. Endocrinological investigations revealed panhypopituitarism. Hypoplasia or aplasia of the pituitary was suspected. Cholestasis and hyperbilirubinemia must be seen in association with growth hormone and cortisol deficiency in the context of pathogenesis.

摘要

本文报告了一例女性新生儿病例,该患儿最初被发现患有严重复发性低血糖症,随后出现胆汁淤积伴结合胆红素血症。未发现传染病、代谢缺陷或肝胆系统疾病。内分泌学检查显示全垂体功能减退。怀疑垂体发育不全或发育不全。在发病机制中,胆汁淤积和高胆红素血症必须与生长激素和皮质醇缺乏相关联。

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