贝纳柯克斯体脂多糖：我们了解多少？
Coxiella burnetii Lipopolysaccharide: What Do We Know?
机构信息
Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK.
Department of Radiotherapy Oncology, CHU de la Timone, Assistance Publique-Hopitaux Marseille, 13385 Marseille, France.
出版信息
Int J Mol Sci. 2017 Nov 23;18(12):2509. doi: 10.3390/ijms18122509.
Abstract
A small gram-negative bacterium, (), is responsible for a zoonosis called Q fever. is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virulence factors, the lipopolysaccharide (LPS) of is one of the major factors involved in this immune hijacking because of its atypical composition and structure. Thus, the aim of this mini-review is to summarize the repressive effects of LPS on the antibacterial immunity of cells.
摘要
一种小的革兰氏阴性细菌，（），是一种称为 Q 热的人畜共患病的病原体。（）是一种细胞内细菌，可以通过劫持免疫系统的几个功能在单核细胞和巨噬细胞等杀菌细胞内生存。在几种毒力因子中，（）的脂多糖（LPS）因其非典型的组成和结构，是参与这种免疫劫持的主要因素之一。因此，本综述的目的是总结（）LPS 对细胞抗菌免疫的抑制作用。
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