Valente Roberto, Sutcliffe Robert, Levesque Eric, Costa Mara, De' Angelis Nicola, Tayar Claude, Cherqui Daniel, Laurent Alexis
Unit of Digestive Surgery, Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Henri Mondor Hospital, Créteil, France; Division of Surgery, University College London, Royal Free Campus, London, UK; HPB Service, Barts Health NHS Trust, London, UK.
Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
HPB (Oxford). 2018 Apr;20(4):347-355. doi: 10.1016/j.hpb.2017.10.006. Epub 2017 Nov 21.
Laparoscopic left hemihepatectomy (LLH) may be an alternative to open (OLH). There are several original variations in the technical aspects of LLH, and no accepted standard. The aim of this study is to assess the safety and effectiveness of the technique developed at Henri Mondor Hospital since 1996.
The technique of LLH was conceived for safety and training of two mature generations of lead surgeons. The technique includes full laparoscopy, ventral approach to the common trunk, extrahepatic pedicle dissection, CUSA parenchymal transection, division of the left hilar plate laterally to the Arantius ligament, and ventral transection of the left hepatic vein. The outcomes of LLH and OLH were compared. Perioperative analysis included intra- and postoperative, and histology variables. Propensity Score Matching was undertaken of background covariates including age, ASA, BMI, fibrosis, steatosis, tumour size, and specimen weight.
17 LLH and 51 OLH were performed from 1996 to 2014 with perioperative mortality rates of 0% and 6%, respectively. In the LLH group, two patients underwent conversion to open surgery. Propensity matching selected 10 LLH/OLH pairs. The LLH group had a higher proportion of procedures for benign disease. LLH was associated with longer operating time and less blood loss. Perioperative complications occurred in 30% (LLH) and 10% (OLH) (p = 1). Mortality and ITU stay were similar.
This technique is recommended as a possible technical reference for standard LLH.
腹腔镜左半肝切除术(LLH)可能是开腹左半肝切除术(OLH)的一种替代方法。LLH在技术方面存在多种原始变体,且尚无公认的标准。本研究的目的是评估自1996年以来在亨利·蒙多医院开展的该技术的安全性和有效性。
LLH技术旨在确保安全并用于培养两代成熟的主刀医生。该技术包括全腹腔镜操作、经腹入路至肝总干、肝外蒂解剖、超声刀实质离断、在肝圆韧带外侧离断左肝门板以及经腹离断左肝静脉。比较了LLH和OLH的手术结果。围手术期分析包括术中、术后及组织学变量。对年龄、美国麻醉医师协会(ASA)分级、体重指数(BMI)、纤维化、脂肪变性、肿瘤大小和标本重量等背景协变量进行倾向得分匹配。
1996年至2014年期间共进行了17例LLH和51例OLH,围手术期死亡率分别为0%和6%。在LLH组中,有2例患者转为开腹手术。倾向得分匹配选出了10对LLH/OLH病例。LLH组中良性疾病手术的比例更高。LLH与手术时间更长和出血量更少相关。围手术期并发症发生率在LLH组为30%,在OLH组为10%(p = 1)。死亡率和重症监护病房(ITU)住院时间相似。
推荐该技术作为标准LLH的一种可能的技术参考。