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Role of Ketamine and Methadone as Adjunctive Therapy in Complex Pain Management: A Case Report and Literature Review.氯胺酮和美沙酮作为辅助疗法在复杂疼痛管理中的作用:病例报告与文献综述
Indian J Palliat Care. 2017 Jan-Mar;23(1):100-103. doi: 10.4103/0973-1075.197956.
2
Regional homogeneity changes between heroin relapse and non-relapse patients under methadone maintenance treatment: a resting-state fMRI study.美沙酮维持治疗下海洛因复吸与未复吸患者之间的局部一致性变化:一项静息态功能磁共振成像研究
BMC Neurol. 2016 Aug 18;16(1):145. doi: 10.1186/s12883-016-0659-3.
3
Drug addiction stigma in relation to methadone maintenance treatment by different service delivery models in Vietnam.越南不同服务提供模式下与美沙酮维持治疗相关的药物成瘾污名化问题。
BMC Public Health. 2016 Mar 8;16:238. doi: 10.1186/s12889-016-2897-0.
4
Cannabis smoke can be a major risk factor for early-age laryngeal cancer--a molecular signaling-based approach.大麻烟雾可能是早发性喉癌的主要风险因素——一种基于分子信号传导的方法。
Tumour Biol. 2015 Aug;36(8):6029-36. doi: 10.1007/s13277-015-3279-4. Epub 2015 Mar 4.
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[Application research on RBH perceptual evaluation of voice disorders].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Jun;48(6):465-9.
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Laryngeal pathologies in older Korean adults and their association with smoking and alcohol consumption.韩国老年人的喉部病变及其与吸烟和饮酒的关系。
Laryngoscope. 2013 Feb;123(2):429-33. doi: 10.1002/lary.23603. Epub 2012 Sep 18.
7
Alcohol consumption after laryngectomy.喉切除术术后饮酒。
Clin Otolaryngol. 2011 Aug;36(4):336-44. doi: 10.1111/j.1749-4486.2011.02355.x.
8
The effect of appraisal level on processing of emotional prosody in meaningless speech.评估水平对无意义言语中情感韵律加工的影响。
Neuroimage. 2008 Aug 15;42(2):919-27. doi: 10.1016/j.neuroimage.2008.05.034. Epub 2008 Jun 30.
9
[On the auditory evaluation of voice quality].[关于嗓音质量的听觉评估]
HNO. 2006 Oct;54(10):793-802. doi: 10.1007/s00106-005-1310-6.
10
[Otorhinolaryngological effects of cocaine and/or crack abuse in drug addicts].[可卡因和/或强效纯可卡因滥用对吸毒者的耳鼻喉科影响]
Rev Assoc Med Bras (1992). 1999 Jul-Sep;45(3):237-41. doi: 10.1590/s0104-42301999000300008.

通过 RBH 量表和客观声学参数对美沙酮治疗成瘾者的嗓音评估。

Vocal assessment of addicts on methadone therapy via the RBH scale and objective acoustic parameters.

机构信息

University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.

University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Clinical Centre of Vojvodina, Otorhinolaryngology Clinic, Department of Phoniatrics, Novi Sad, Serbia.

出版信息

Braz J Otorhinolaryngol. 2019 Jan-Feb;85(1):50-54. doi: 10.1016/j.bjorl.2017.10.008. Epub 2017 Nov 10.

DOI:10.1016/j.bjorl.2017.10.008
PMID:29174584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9442897/
Abstract

INTRODUCTION

A large number of people around the world struggle daily to become free of their addiction to illegal psychoactive substances. In order to create an atmosphere of improved supervision, established communication and improved quality of life for drug addicts, centers have been set up to provide methadone as a substitute.

OBJECTIVE

The aim of the research was to assess the vocal features of drug addicts on methadone therapy via subjective and objective parameters, to ascertain if vocal damage has occurred and to determine whether subjective and objective acoustic vocal parameters are related, and how.

METHODS

The research included 34 adults of both genders who were undergoing methadone treatment. A subjective vocal evaluation assessed voice pitch and clarity, while the subjective acoustic analysis utilized the Roughness-Breathiness-Hoarseness scale of roughness-breathiness-hoarseness. Objective acoustic analysis was conducted after recording and analyzing an uninterrupted vocal /a/ of at least three seconds duration, using the "GllotisController" software.

RESULTS

The subjective acoustic analysis using the Roughness-Breathiness-Hoarseness scale showed pathological values in 52.9% male and 47% female participants. The average values of the roughness-breathiness-hoarseness for the entire sample were 0.91, 0.38 and 0.50, respectively. Lower roughness was associated with a higher fundamental frequency (f) and lower jitter and shimmer values (p<0.05). There was a statistically significant correlation between breathiness, jitter (p<0.01) and shimmer (p<0.05), and between hoarseness and jitter (p<0.01).

CONCLUSION

A statistically significant correlation was found between the two subjective vocal assessments, voice clarity and pitch, and Roughness-Breathiness-Hoarseness scale, and the parameters of the objective acoustic vocal assessment.

摘要

简介

全球有大量的人每天都在努力摆脱对非法精神活性物质的依赖。为了营造加强监管、建立沟通和改善吸毒者生活质量的氛围,设立了中心,提供美沙酮作为替代物。

目的

本研究旨在通过主观和客观参数评估接受美沙酮治疗的吸毒者的嗓音特征,确定是否发生了嗓音损伤,并确定主观和客观声学嗓音参数之间的关系及其方式。

方法

该研究纳入了 34 名正在接受美沙酮治疗的成年人,包括男性和女性。主观嗓音评估评估了嗓音音高和清晰度,而主观声学分析则使用了粗糙度-呼吸度-糙度的粗糙度-呼吸度-糙度量表。在录制和分析至少 3 秒的不间断/a/音后,使用“GllotisController”软件进行客观声学分析。

结果

使用粗糙度-呼吸度-糙度量表进行的主观声学分析显示,52.9%的男性和 47%的女性参与者存在病理性值。整个样本的粗糙度-呼吸度-糙度平均值分别为 0.91、0.38 和 0.50。粗糙度越低,基频(f)越高,抖动和闪烁值越低(p<0.05)。呼吸度、抖动(p<0.01)和闪烁(p<0.05)之间以及糙度和抖动(p<0.01)之间存在统计学显著相关性。

结论

在主观嗓音评估的两个参数,即清晰度和音高,以及粗糙度-呼吸度-糙度量表,以及客观声学嗓音评估的参数之间,发现了统计学上显著的相关性。