Faisal Wasek, Jacques Judith
Department of Medical Oncology, Ballarat Regional Integrated Cancer Centre, Ballarat, Victoria, Australia.
Department of Palliative Care, Central Coast Cancer Centre, Gosford, NSW, Australia.
Indian J Palliat Care. 2017 Jan-Mar;23(1):100-103. doi: 10.4103/0973-1075.197956.
Assessment and management of complex cancer pain always remains a major challenge for any palliative care team, given its heterogeneity of underlying pathophysiology and limitations of any pharmacotherapy. Here, we present a case of complex pain management in a young patient with a life-limiting illness, highlighting the issues of organic and nonorganic contributors of pain and provide some insight into the role of ketamine and methadone as adjunctive therapy to opioid analgesics. A brief literature review is also done to provide the context of use of these adjunctive drugs in this setting.
鉴于复杂癌症疼痛潜在病理生理学的异质性以及任何药物治疗的局限性，对任何姑息治疗团队而言，其评估和管理始终是一项重大挑战。在此，我们介绍一例患有危及生命疾病的年轻患者的复杂疼痛管理病例，突出疼痛的器质性和非器质性因素问题，并深入探讨氯胺酮和美沙酮作为阿片类镇痛药辅助治疗的作用。我们还进行了简要的文献综述，以提供在这种情况下使用这些辅助药物的背景信息。
