Adedeji M O
East Afr Med J. 1989 Jan;66(1):64-8.
Forty-three adult cases of acute leukaemia (AL) seen at the University of Benin Teaching Hospital, Benin City, Nigeria in the 13-year period 1975-1987 have been analysed with respect to the presenting features, management and outcome. The percentage incidence of AML and ALL were 51.2 and 23.3 respectively. There is a preponderance of male patient (male:female ratio was 2.1:1, 2.3:1, 1.3:1, and 3:1 respectively for AML, ALL, BC and ALSCL). Most cases of AL occurred in the 21-30-year age bracket. Pallor (77.3%) is the commonest presenting feature in AML whereas night sweats and lymphadenopathy occurred in most cases of ALL (80%). The main causes of death are haemorrhage and infection. Treatment is generally inadequate and so the results of treatment are poor.
对1975年至1987年这13年间在尼日利亚贝宁城贝宁大学教学医院收治的43例成人急性白血病(AL)病例的临床表现、治疗及转归进行了分析。急性髓系白血病(AML)和急性淋巴细胞白血病(ALL)的发病率分别为51.2%和23.3%。男性患者居多(AML、ALL、急性髓系白血病伴骨髓增殖异常相关改变(BC)和急性淋巴细胞白血病伴成熟型(ALSCL)的男女比例分别为2.1:1、2.3:1、1.3:1和3:1)。大多数AL病例发生在21至30岁年龄组。面色苍白(77.3%)是AML最常见的临床表现,而盗汗和淋巴结病在大多数ALL病例中出现(80%)。主要死亡原因是出血和感染。治疗普遍不足,因此治疗效果较差。