与转移性黑色素瘤相关的副肿瘤性卵黄样黄斑病变
PARANEOPLASTIC VITELLIFORM MACULOPATHY ASSOCIATED WITH METASTATIC MELANOMA.
作者信息
Rahimi Mansour, Navajas Eduardo V, Sarraf David
机构信息
Department of Ophthalmology, Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Department of Ophthalmology & Visual Sciences, The University of British Columbia, Vancouver, British Columbia, Canada.
出版信息
Retin Cases Brief Rep. 2018;12 Suppl 1:S102-S104. doi: 10.1097/ICB.0000000000000660.
PURPOSE
To report a case of paraneoplastic vitelliform maculopathy in a patient with metastatic melanoma of unknown primary site.
METHODS
Case report. Main outcome measures include funduscopic examination, fluorescein angiography, fundus autofluorescence, and spectral domain optical coherence tomography.
RESULTS
A 44-year-old man with a known history of metastatic melanoma was referred for ophthalmic evaluation because of bilateral vision loss. Funduscopic examination was remarkable for vitelliform maculopathy that was confirmed with fundus autofluorescence and spectral domain optical coherence tomography.
CONCLUSION
We describe a rare case of paraneoplastic vitelliform maculopathy. There are many etiologies of acquired vitelliform retinal lesions in the retina. Multimodal retinal imaging, including fundus autofluorescence and spectral domain optical coherence tomography, can be best used to identify these lesions. A history of systemic metastatic melanoma should be ruled out in patients with vitelliform maculopathy.
目的
报告一例原发部位不明的转移性黑色素瘤患者并发副肿瘤性卵黄样黄斑病变的病例。
方法
病例报告。主要观察指标包括眼底检查、荧光素血管造影、眼底自发荧光和频域光学相干断层扫描。
结果
一名有转移性黑色素瘤病史的44岁男性因双眼视力丧失前来眼科评估。眼底检查发现卵黄样黄斑病变，经眼底自发荧光和频域光学相干断层扫描得以确诊。
结论
我们描述了一例罕见的副肿瘤性卵黄样黄斑病变病例。视网膜后天性卵黄样视网膜病变有多种病因。包括眼底自发荧光和频域光学相干断层扫描在内的多模式视网膜成像最有助于识别这些病变。卵黄样黄斑病变患者应排除系统性转移性黑色素瘤病史。
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