Williams Steven L, McDonald H Richard, Jumper J Michael, Fu Arthur D, Lujan Brandon J, Cunningham Emmett T, Johnson Robert N
*Pacific Vision Foundation, California Pacific Medical Center, San Francisco, California; †West Coast Retina Medical Group, San Francisco, California; and ‡Department of Ophthalmology, Stanford University School of Medicine, Stanford, California.
Retin Cases Brief Rep. 2014 Fall;8(4):269-72. doi: 10.1097/ICB.0000000000000098.
To describe a peculiar case of paraneoplastic vitelliform maculopathy/retinopathy in a patient with treated choroidal melanoma.
A case report of a 58-year-old woman with a history of treated choroidal melanoma 16 years before developing visual changes in the setting of metastatic choroidal melanoma.
We demonstrate bilateral, multifocal vitelliform subretinal lesions and focal, neurosensory retinal detachment associated with metastatic melanoma.
Paraneoplastic vitelliform maculopathy/retinopathy should be considered in patients with or without a history of melanoma, who have unexplained serous, vitelliform retinal detachments, especially with atypical or absence of leakage on fluorescein angiography.
描述一例经治疗的脉络膜黑色素瘤患者发生的副肿瘤性卵黄样黄斑病变/视网膜病变的特殊病例。
一名58岁女性的病例报告,该患者在发生转移性脉络膜黑色素瘤导致视力改变前16年有脉络膜黑色素瘤治疗史。
我们证实了与转移性黑色素瘤相关的双侧、多灶性卵黄样视网膜下病变以及局灶性神经感觉性视网膜脱离。
对于有或无黑色素瘤病史、出现无法解释的浆液性、卵黄样视网膜脱离的患者,尤其是荧光素血管造影显示非典型渗漏或无渗漏的患者,应考虑副肿瘤性卵黄样黄斑病变/视网膜病变。