梅毒性脉络膜视网膜炎自发改善：病例报告及文献复习。

SPONTANEOUS IMPROVEMENT OF SYPHILIS CHORIORETINITIS: CASE REPORT AND REVIEW OF THE LITERATURE.

机构信息

Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Retin Cases Brief Rep. 2020 Spring;14(2):170-173. doi: 10.1097/ICB.0000000000000670.

DOI:10.1097/ICB.0000000000000670

PMID:29176535

Abstract

PURPOSE

To describe a case of spontaneous improvement of syphilis chorioretinitis and review the literature.

METHODS

Case report and literature review of cases with untreated syphilis chorioretinitis.

RESULTS

A 58-year-old man presented to the emergency department with counting fingers vision, normal fundus, and disruption of the outer retinal layers on optical coherence tomography of the right eye. Examination by a retina specialist 3 weeks later revealed visual acuity of 20/50 and partial restoration of outer retinal layers on optical coherence tomography. Workup showed positive serology for syphilis and human immunodeficiency virus. Treatment with intravenous penicillin resulted in further vision improvement. Literature review showed six cases of spontaneous improvement of syphilis chorioretinitis.

CONCLUSION

Spontaneous improvement of syphilis chorioretinitis is possible. Clinicians should keep a high index of suspicion and consider syphilis chorioretinitis in diseases that affect the outer retina even with spontaneous improvement.

摘要

目的

描述一例梅毒性脉络膜视网膜炎的自发改善，并复习相关文献。

方法

对未经治疗的梅毒性脉络膜视网膜炎病例进行病例报告和文献复习。

结果

一名 58 岁男性因视力仅能数指而到急诊就诊，眼底正常，右眼光学相干断层扫描显示外视网膜层中断。3 周后由视网膜专家进行检查，发现视力为 20/50，外视网膜层在光学相干断层扫描上部分恢复。检查显示梅毒和人类免疫缺陷病毒血清学阳性。静脉注射青霉素治疗后视力进一步改善。文献复习显示 6 例梅毒性脉络膜视网膜炎自发改善。