静脉注射肝素导致的皮肤坏死。

Skin necrosis due to intravenous heparin.

作者信息

Rongioletti F, Pisani S, Ciaccio M, Rebora A

机构信息

Department of Dermatology, University of Genoa, Italy.

出版信息

Dermatologica. 1989;178(1):47-50. doi: 10.1159/000248387.

DOI:10.1159/000248387

PMID:2917680

Abstract

A patient on intravenous heparin is described who developed an acute hemorrhagic necrosis of her legs. Thrombi without vasculitis were seen in the dermal blood vessels. This appears to be the 4th reported case of skin necrosis after intravenous heparin at sites unrelated to injections. Skin necrosis after intravenous heparin should warn the dermatologist of a possible fatal outcome from myocardial or cerebral infarction.

摘要

本文描述了一名接受静脉注射肝素治疗的患者，该患者腿部出现急性出血性坏死。在真皮血管中发现了无血管炎的血栓。这似乎是第4例报告的静脉注射肝素后在与注射部位无关的部位发生皮肤坏死的病例。静脉注射肝素后出现皮肤坏死应提醒皮肤科医生注意心肌梗死或脑梗死可能导致的致命后果。