发展一种高分辨率红外热成像方法作为一种诊断小儿急性非特异性跛行的工具。
Development of a high-resolution infrared thermographic imaging method as a diagnostic tool for acute undifferentiated limp in young children.
机构信息
The University of Sheffield Medical School, Sheffield, UK.
Sheffield Children's NHS Foundation Trust, Sheffield, UK.
出版信息
Med Biol Eng Comput. 2018 Jun;56(6):1115-1125. doi: 10.1007/s11517-017-1749-0. Epub 2017 Nov 28.
Acute limp is a common presenting condition in the paediatric emergency department. There are a number of causes of acute limp that include traumatic injury, infection and malignancy. These causes in young children are not easily distinguished. In this pilot study, an infrared thermographic imaging technique to diagnose acute undifferentiated limp in young children was developed. Following required ethics approval, 30 children (mean age = 5.2 years, standard deviation = 3.3 years) were recruited. The exposed lower limbs of participants were imaged using a high-resolution thermal camera. Using predefined regions of interest (ROI), any skin surface temperature difference between the healthy and affected legs was statistically analysed, with the aim of identifying limp. In all examined ROIs, the median skin surface temperature for the affected limb was higher than that of the healthy limb. The small sample size recruited for each group, however, meant that the statistical tests of significant difference need to be interpreted in this context. Thermal imaging showed potential in helping with the diagnosis of acute limp in children. Repeating a similar study with a larger sample size will be beneficial to establish reproducibility of the results. Graphical abstract A young child with an acute undifferentiated limp undergoes thermal imaging and the follow on image analysis assists the limp diagnosis.
急性跛行是儿科急诊室常见的就诊症状。引起急性跛行的原因有很多,包括创伤、感染和恶性肿瘤。这些原因在幼儿中不易区分。在这项初步研究中,开发了一种红外热成像技术来诊断幼儿急性未分化跛行。在获得所需的伦理批准后,招募了 30 名儿童(平均年龄= 5.2 岁,标准差= 3.3 岁)。使用高分辨率热像仪对参与者的下肢进行成像。使用预定义的感兴趣区域(ROI),对健康腿和患腿之间的任何皮肤表面温差进行统计学分析,目的是确定跛行。在所有检查的 ROI 中,患侧肢体的皮肤表面温度中位数高于健侧肢体。然而,由于每组招募的样本量都很小,因此需要在这种情况下解释统计检验的显著性差异。热成像显示出在帮助诊断儿童急性跛行方面的潜力。用更大的样本量重复进行类似的研究将有助于确定结果的可重复性。
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