a Department of Physiology, Medical Faculty , Medical University , Plovdiv , Bulgaria.
b Department of Clinical Laboratory, Medical Faculty , Medical University , Plovdiv , Bulgaria.
Arch Physiol Biochem. 2018 Oct;124(4):357-360. doi: 10.1080/13813455.2017.1408661. Epub 2017 Nov 28.
To examine some anthropometric parameters, arterial stiffness, lipid profile, and soluble adhesion molecules in young adults with reduced physical activity.
The study is carried on 54 healthy young adults aged 20.97 ± 2.04 years. Two groups: 23 with reduced physical activity (INAC) and 31 with optimal physical activity (AC). Body mass index (BMI), basal metabolic rate (BMR), central aortic systolic blood pressure (CSBP, mmHg), plasma atherogenic index (AIP), and serum soluble cell adhesion molecules (sICAM-1, sVCAM-1) are followed up.
CSBP [115.56 ± 10.22 vs. 105.13 ± 9.88*], AIP [-0.04 ± 0.18 vs. -0.08 ± 0.08**] and sICAM-1 [362.5 ± 49.95 vs. 281.75 ± 80.39**] are significantly higher, and BMR [1431 ± 297.9 vs. 1674.6 ± 365.57*] is significantly lower in the physically inactive young healthy adults.
CSBP, AIP, and sICAM-1 are higher in young adults with reduced physical activity. This plays substantial role in the acceleration of atherogenic process and in long-term perspective could promote cardiovascular diseases.
研究体力活动减少的年轻成年人的一些人体测量参数、动脉僵硬度、血脂谱和可溶性黏附分子。
本研究纳入了 54 名年龄为 20.97±2.04 岁的健康年轻成年人。将他们分为两组：23 名体力活动减少的（INAC）和 31 名体力活动正常的（AC）。监测体质量指数（BMI）、基础代谢率（BMR）、中心主动脉收缩压（CSBP，mmHg）、血浆致动脉粥样硬化指数（AIP）和血清可溶性细胞黏附分子（sICAM-1、sVCAM-1）。
CSBP[115.56±10.22 比 105.13±9.88*]、AIP[-0.04±0.18 比-0.08±0.08**]和 sICAM-1[362.5±49.95 比 281.75±80.39**]明显更高，BMR[1431±297.9 比 1674.6±365.57*]明显更低。
体力活动减少的年轻健康成年人的 CSBP、AIP 和 sICAM-1 更高。这在动脉粥样硬化过程的加速中起着重要作用，从长远来看可能会促进心血管疾病的发生。
