Ahmadi Fariba, Zarei Ehsan
Deputy of Health Affairs, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Public Health, School of Health, Shahid Beheshti University of Medical Sciences, Velenjak, Tehran, Iran.
BMC Public Health. 2017 Nov 28;17(1):908. doi: 10.1186/s12889-017-4932-1.
The inappropriate use of drugs due to irrational prescriptions is a common problem in Iran, but there is little evidence of prescription patterns in rural family physicians. This study aimed to explore the prescribing pattern and rational drug use indicators for family physicians using Index of Rational Drug Prescribing (IRDP) in Kermanshah Province, Iran.
In this retrospective study, 352,399 prescriptions from 184 family physicians in 103 primary health care (PHC) centers were examined. As stated, an analysis was done for rational use indicators suggested by World Health Organization (WHO): e.g., the percentage of prescriptions containing antibiotics, injections, and those prescribed by a generic name and from a national essential medicine list, plus the average number of drugs per prescription; these factors were all taken into account. Rational drug use was studied with the IRDP.
The average number of drugs per prescription was 3.14 (± 1.2) and the average cost per prescription was 116,740 IRR (USD 3.6). Around 19% of prescriptions had more than four drugs, while the percentage of prescriptions involving antibiotics and injections was 52.1% and 24.4%, respectively. There was 95.1% drugs prescribed by their generic name and 95.9% were retrieved from the essential drugs list. The value of the IRDP was 3.70 out of 5.
The findings of this study showed that some degree of irrational drug prescribing exists among family physicians, especially in terms of injections, antibiotics, and polypharmacy. It is recommended that there be continuing education programs for physicians regarding rational prescribing for different kinds of medical indications. Clinical practice guidelines should also assist with the rational use of medicine.
由于不合理处方导致的药物使用不当是伊朗的一个常见问题,但关于农村家庭医生处方模式的证据很少。本研究旨在探讨伊朗克尔曼沙阿省家庭医生使用合理用药处方指数(IRDP)的处方模式和合理用药指标。
在这项回顾性研究中,检查了103个初级卫生保健(PHC)中心的184名家庭医生的352399张处方。如前所述,对世界卫生组织(WHO)建议的合理用药指标进行了分析:例如,含有抗生素、注射剂的处方百分比,以及使用通用名开具的处方和来自国家基本药物清单的处方百分比,再加上每张处方的平均药物数量;所有这些因素都被考虑在内。使用IRDP研究合理用药情况。
每张处方的平均药物数量为3.14(±1.2),每张处方的平均费用为116740伊朗里亚尔(3.6美元)。约19%的处方有四种以上药物,而涉及抗生素和注射剂的处方百分比分别为52.1%和24.4%。95.1%的药物使用通用名开具,95.9%的药物来自基本药物清单。IRDP的值为3.70(满分5分)。
本研究结果表明,家庭医生中存在一定程度的不合理用药情况,尤其是在注射剂、抗生素和多药联用方面。建议为医生开展关于针对不同医学适应症合理处方的继续教育项目。临床实践指南也应有助于合理用药。