Manirakiza Audace, Gitonga Nyamu David, Maru Shital Mahindra, Bizimana Thomas, Nimpagaritse Manassé
Master of Health Supply Chain Management at the East African Community Regional Centre of Excellence for Vaccines, Immunization, and Health Supply Chain Management, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Department of Pharmacology, Clinical Pharmacy and Pharmacy Practice, Faculty of Health Sciences, University of Naïrobi, Nairobi, Kenya.
J Pharm Policy Pract. 2024 Feb 29;17(1):2312369. doi: 10.1080/20523211.2024.2312369. eCollection 2024.
Rational prescribing is key to optimising therapeutic outcomes and avoiding risks associated with irrational use of medicines. Using WHO drug use indicators, this study evaluated drug use patterns among paediatric outpatient encounters at Primary Healthcare Centers (PHCs) in Bujumbura Mairie, Republic of Burundi.
Descriptive cross-sectional research assessed paediatric medicine use in 20 PHCs. From 8 February to 7 April 2023, 800 randomly selected paediatric encounters' 2022-year data were retrospectively collected. Data for specific facility indicators were prospectively collected. SPSS 23 was used to analyse data.
800 outpatient child encounters were analysed, 48.4% female and 51.6% male. The mean number of medicines per encounter was 2.4(±0.99). The injection rate was 9.9%. Overall, 78.8% of generics and 85.2% of essential medicines were prescribed. Results show drug prescribing differences between private and government PHCs (< 0.001). All PHCs studied had no standard treatment guidelines (STGs), while 50% had an essential medicine list (EML) and 85% of key medicines were available.
Poor prescribing practices were found indicating the need for interventions to promote good drug use practices. A large study at a national scale is required to provide a more comprehensive understanding of the overall drug use practices.
合理用药是优化治疗效果和避免不合理用药风险的关键。本研究使用世界卫生组织的药物使用指标,评估了布隆迪共和国布琼布拉市初级卫生保健中心(PHCs)儿科门诊就诊中的用药模式。
描述性横断面研究评估了20个初级卫生保健中心的儿科用药情况。2023年2月8日至4月7日,回顾性收集了随机选取的800例儿科就诊病例2022年的数据。前瞻性收集特定机构指标的数据。使用SPSS 23进行数据分析。
分析了800例门诊儿童就诊病例,其中女性占48.4%,男性占51.6%。每次就诊的平均用药数量为2.4(±0.99)。注射率为9.9%。总体而言,78.8%的药品为仿制药,85.2%的药品为基本药物。结果显示私立和政府初级卫生保健中心之间的药物处方存在差异(<0.001)。所有研究的初级卫生保健中心均无标准治疗指南(STGs),而50%有基本药物清单(EML),85%的关键药物有供应。
发现存在不良的处方行为,表明需要采取干预措施来促进良好的用药习惯。需要在全国范围内进行大规模研究,以更全面地了解总体用药情况。