新辅助治疗策略：先进的放疗替代方案
Neoadjuvant Treatment Strategies: Advanced Radiation Alternatives.
作者信息
Minsky Bruce D
机构信息
Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
出版信息
Clin Colon Rectal Surg. 2017 Nov;30(5):377-382. doi: 10.1055/s-0037-1606115. Epub 2017 Nov 27.
Abstract
Long-course chemoradiation therapy (CRT) has been the standard approach for locally advanced rectal tumors. Neoadjuvant CRT is associated to improved local disease control, with less toxicity when compared with adjuvant CRT, as well as the chance for pathologic complete response. The CRT regimens have improved over the past years. This article will examine selected controversies, including novel chemoradiation regimens, duration of radiation (short vs. long course), and radiation techniques such as intensity-modulated radiation therapy (IMRT).
摘要
长疗程放化疗（CRT）一直是局部晚期直肠癌的标准治疗方法。新辅助CRT与改善局部疾病控制相关，与辅助CRT相比毒性更小，并且有获得病理完全缓解的机会。在过去几年中，CRT方案已经有所改进。本文将探讨一些选定的争议问题，包括新型放化疗方案、放疗疗程（短疗程与长疗程）以及诸如调强放疗（IMRT）等放疗技术。
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