Khan Faizan Ahmed, Parayaruthottam Prathapan, Roshan Gazanafer, Menon Vineeth, Fidha Mariyam, Fernandes Anthony Kevin
Department of Orthodontics, Yenepoya Dental College, Mangalore, Karnataka, India.
Department of Orthodontics, Government Dental College, Thrissur, Kerala, India.
J Int Soc Prev Community Dent. 2017 Oct;7(Suppl 2):S55-S60. doi: 10.4103/jispcd.JISPCD_284_17. Epub 2017 Oct 30.
Advancing research in medicine and technology has benefitted the mankind immensely with its contribution toward an improved life quality and increased life expectancy. The inability of a human body to autoregenerate has resulted in an increased demand for newer and healthier tissues and organs. Therefore, the restoration of naturally replicated tissue components has become a subject of interest for the scientific community lately. There was felt an intense quest for promoting strategies that could restore tissue regeneration and fuel the field of regenerative medicine. It was then the role of platelets was accounted for its wound healing and regenerative effects. Consequently, the use of platelet concentrates to improve wound healing, and bone formation was explored, which was considered to be possible because platelets contain high quantities of growth factors which would be able to stimulate cell proliferation, matrix remodeling, and angiogenesis, thereby establishing a new era of research with the successful application of innovative medical therapies focused on healing damaged tissues or regenerate the affected organs.
医学和技术研究的进步通过对提高生活质量和延长预期寿命的贡献,极大地造福了人类。人体无法自我再生导致对更新、更健康的组织和器官的需求增加。因此,恢复自然复制的组织成分最近已成为科学界感兴趣的课题。人们强烈寻求能够促进组织再生并推动再生医学领域发展的策略。当时,血小板因其伤口愈合和再生作用而受到关注。因此,人们探索了使用血小板浓缩物来改善伤口愈合和促进骨形成,这被认为是可行的,因为血小板含有大量生长因子,能够刺激细胞增殖、基质重塑和血管生成,从而通过成功应用专注于修复受损组织或再生受影响器官的创新医学疗法,开创了一个新的研究时代。