Baniasadi Behrang, Evrard Laurence
Department of Maxillofacial Surgery and Dentistry, Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
Open Dent J. 2017 Feb 14;11:99-108. doi: 10.2174/1874210601711010099. eCollection 2017.
The purpose of this study was to evaluate vertical alveolar bone loss 3 months after tooth extraction when a technique of ridge preservation was applied using a particulate demineralized freeze-dried bone allograft 300 - 500 µm associated with platelet concentrates (platelet-rich-fibrin) in the form of gel and membranes.
A retrospective radiological clinical study was conducted on 56 patients for whom 95 extractions had been performed immediately followed by alveolar filling. Among the patients, 17 were smokers and 16 were provided with an immediate removable temporary prosthesis after extractions. Vertical bone loss was measured radiologically by panoramic X-ray before extractions and by a computed tomography scan 3 months after, at the level of mid-buccal bone wall, by two independent observers. For statistical analysis, Student's t-test was performed to compare the mean bone loss between mono- and pluri-radicular teeth and to compare the mean bone loss between tobacco users non users and finally to compare the mean bone loss between individuals that had provisional removable prosthesis and those that had not.
Three months after tooth extraction, the mean of vertical loss of the mid-buccal bone wall was 0.72 (SD 0.71) mm (5.53% SD 5.19). No significant difference between bone loss at mono-radicular and pluri-radicular teeth (P = 0.982) was observed. There was no significant correlation between tobacco habits and bone loss (P = 0.2), nor between provisional removable prosthesis and bone loss (P = 0.786).
These results indicate a good potential for the technique using Demineralized Freeze-Dried Bone Allograft 300 - 500 µm and platelet concentrates in alveolar bone preservation.
本研究的目的是评估在采用一种牙槽嵴保存技术时，即使用300 - 500微米的颗粒状脱矿冻干同种异体骨，并结合凝胶和膜形式的血小板浓缩物（富血小板纤维蛋白），拔牙后3个月时垂直牙槽骨吸收的情况。
对56例患者进行了一项回顾性放射临床研究，这些患者共接受了95次拔牙，拔牙后立即进行牙槽骨填充。患者中，17例为吸烟者，16例拔牙后佩戴了即刻可摘临时义齿。由两名独立观察者在拔牙前通过全景X线片以及拔牙后3个月通过计算机断层扫描在颊侧骨壁中部水平进行放射学测量垂直骨吸收情况。进行统计学分析时，采用学生t检验来比较单根牙和多根牙之间的平均骨吸收情况，比较吸烟患者和非吸烟患者之间的平均骨吸收情况，最后比较佩戴临时可摘义齿者和未佩戴者之间的平均骨吸收情况。
拔牙后3个月，颊侧骨壁中部垂直骨吸收的平均值为0.72（标准差0.71）毫米（5.53%，标准差5.19）。单根牙和多根牙的骨吸收之间未观察到显著差异（P = 0.982）。吸烟习惯与骨吸收之间无显著相关性（P = 0.2），临时可摘义齿与骨吸收之间也无显著相关性（P = 0.786）。
这些结果表明，使用300 - 500微米脱矿冻干同种异体骨和血小板浓缩物的技术在牙槽骨保存方面具有良好的潜力。
