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Biochemical Basis of Vosevi, a New Treatment for Hepatitis C.

作者信息

Besandre Ronald, Liu Hung-Wen

机构信息

Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, and Department of Chemistry, The University of Texas at Austin , Austin, Texas 78712, United States.

出版信息

Biochemistry. 2018 Feb 6;57(5):479-480. doi: 10.1021/acs.biochem.7b01157. Epub 2017 Nov 29.

Abstract
摘要

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本文引用的文献

1
Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection.
N Engl J Med. 2017 Jun 1;376(22):2134-2146. doi: 10.1056/NEJMoa1613512.
2
Global epidemiology and burden of HCV infection and HCV-related disease.
Nat Rev Gastroenterol Hepatol. 2017 Feb;14(2):122-132. doi: 10.1038/nrgastro.2016.176. Epub 2016 Dec 7.
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Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights.
Nat Rev Gastroenterol Hepatol. 2016 Jun;13(6):338-51. doi: 10.1038/nrgastro.2016.60. Epub 2016 May 5.
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Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase.
Science. 2015 Feb 13;347(6223):771-5. doi: 10.1126/science.1259210.
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Discovery and development of hepatitis C virus NS5A replication complex inhibitors.
J Med Chem. 2014 Mar 13;57(5):1643-72. doi: 10.1021/jm401793m. Epub 2014 Feb 3.

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