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经尿道膀胱途径取卵:在肿瘤生育力保护中,老技术新适应证。

Perurethral transvesical route for oocytes retrieval: an old technique for a new indication in oncofertility.

机构信息

ART Center Aziza Othmana Hospital, Faculté de Médecine de Tunis, Université de Tunis El Manar, 1008, Tunis, Tunisia.

ART Departement of Reproductive Biology & Cytogenetics, Faculté de Médecine de Tunis, Université de Tunis El Manar, 1008, Tunis, Tunisia.

出版信息

Future Oncol. 2017 Dec;13(28):2547-2553. doi: 10.2217/fon-2017-0276. Epub 2017 Nov 30.

Abstract

UNLABELLED

We aimed to evaluate the safety and efficiency of the peruretheral transvesical oocyte retrieval in oncofertility. We conducted a retrospective comparative study in our assisted reproductive technologies center.

STUDY GROUP

28 pubertal young women affected by malignancies, referred for fertility preservation and refusing transvaginal (TV) procedure.

CONTROL GROUP

28 infertile patients, aged less than 25 years, who have undergone in vitro fertilization with TV oocyte retrieval. The ovarian stimulation was significantly longer on the study group. There was no difference between the two groups regarding mean number of collected metaphase II oocytes. One patient of the study group had a transient dysuria. These preliminary data suggest that, in oncofertility, peruretheral transvesical oocyte retrieval is an alternative when the TV route is refused or not feasible.

摘要

目的

评估经尿道膀胱外途径取卵术用于肿瘤患者保留生育力的安全性和有效性。方法:回顾性比较研究。

研究组

28 例青春期女性恶性肿瘤患者,因生育力保存而拒绝行经阴道(TV)取卵术。

对照组

28 例年龄<25 岁的不孕患者,行 TV 取卵术行体外受精。研究组的卵巢刺激时间明显更长。两组间获成熟 II 期卵母细胞的平均数无差异。研究组 1 例患者出现短暂性尿痛。这些初步数据表明,在肿瘤患者保留生育力方面,当 TV 途径被拒绝或不可行时,经尿道膀胱外途径取卵术是一种替代方法。

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