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Crit Care Med. 2017 May;45(5):843-850. doi: 10.1097/CCM.0000000000002330.
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Oxygen: Breath of Life or Kiss of Death.氧气：生命的气息还是死亡之吻。
Crit Care Med. 2017 Feb;45(2):368-369. doi: 10.1097/CCM.0000000000002113.
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Effects of neuromuscular blockers on transpulmonary pressures in moderate to severe acute respiratory distress syndrome.神经肌肉阻滞剂对中重度急性呼吸窘迫综合征患者跨肺压的影响。
Intensive Care Med. 2017 Mar;43(3):408-418. doi: 10.1007/s00134-016-4653-4. Epub 2016 Dec 24.
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Looking closer at acute respiratory distress syndrome: the role of advanced imaging techniques.深入了解急性呼吸窘迫综合征：高级影像学技术的作用。
Curr Opin Crit Care. 2017 Feb;23(1):30-37. doi: 10.1097/MCC.0000000000000380.
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Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial.保守与常规吸氧治疗对重症监护病房患者死亡率的影响：氧气 ICU 随机临床试验。
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Airway driving pressure and lung stress in ARDS patients.急性呼吸窘迫综合征患者的气道驱动压与肺应力
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Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial.急性呼吸窘迫综合征的开放肺通气方法：一项初步随机对照试验
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8
Recruitment Maneuvers and Positive End-Expiratory Pressure Titration in Morbidly Obese ICU Patients.肥胖 ICU 患者的募集手法和呼气末正压滴定。
Crit Care Med. 2016 Feb;44(2):300-7. doi: 10.1097/CCM.0000000000001387.
9
Assessment of PaO₂/FiO₂ for stratification of patients with moderate and severe acute respiratory distress syndrome.评估氧合指数（PaO₂/FiO₂）用于中重度急性呼吸窘迫综合征患者的分层。
BMJ Open. 2015 Mar 27;5(3):e006812. doi: 10.1136/bmjopen-2014-006812.
10
Driving pressure and survival in the acute respiratory distress syndrome.驱动压与急性呼吸窘迫综合征患者的生存。
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持续性低氧血症的管理：有哪些新进展？

Managing Persistent Hypoxemia: what is new?

作者信息

Villar Jesús, Ferrando Carlos, Kacmarek Robert M

机构信息

Keenan Research Center for Biomedical Science at the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.

Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.

出版信息

F1000Res. 2017 Nov 13;6:1993. doi: 10.12688/f1000research.11760.1. eCollection 2017.

DOI:10.12688/f1000research.11760.1
PMID:29188024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5686475/
Abstract

Mechanical ventilation is the standard life-support technique for patients with severe acute respiratory failure. However, some patients develop persistent and refractory hypoxemia because their lungs are so severely damaged that they are unable to respond to the application of high inspired oxygen concentration and high levels of positive end-expiratory pressure. In this article, we review current knowledge on managing persistent hypoxemia in patients with injured lungs.

摘要

机械通气是重症急性呼吸衰竭患者的标准生命支持技术。然而，一些患者会出现持续性难治性低氧血症，因为他们的肺部严重受损，无法对高吸入氧浓度和高水平呼气末正压的应用做出反应。在本文中，我们综述了目前关于处理肺损伤患者持续性低氧血症的知识。