Kieran F. Reid, PhD, MPH, Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA. Email:
J Prev Alzheimers Dis. 2017;4(1):44-50. doi: 10.14283/jpad.2016.107.
We examined whether multiple domains of baseline cognitive performance were associated with prospective physical activity (PA) adherence in the Lifestyle Interventions and Independence for Elders Pilot study (LIFE-P).
DESIGN, SETTING, PARTICIPANTS: The LIFE-P study was a single-blind, multicenter, randomized controlled trial of a PA intervention compared to a successful aging educational intervention in sedentary, mobility-limited older adults.
A 12-month structured, moderate-intensity, multi-modal PA program that included walking, resistance training, and flexibility exercises. For the first 2 months (adoption), 3 center-based exercise sessions (40-60 min) / week were conducted. During the next 4 months (transition), center-based sessions were conducted 2 times / week. The subsequent maintenance phase consisted of optional once-to-twice-per-week center-based sessions and home-based PA.
Tests of executive and global cognitive functioning, working memory and psychomotor speed were administered at baseline. Median test scores were used to dichotomize participants into low or high cognitive performance groups.
52 mobility-limited older adults (age: 76.9 ±5 yrs) were randomized to the PA arm of LIFE-P. Compared to participants with high cognitive performance, participants with low performance had similar PA adherence rates (all P ≥ 0.34). Furthermore, weak and non-significant univariate relationships were elicited between all measures of cognition and overall PA adherence levels (r values ranged: -0.20 to 0.12, P ≥ 0.12).
These data suggest that cognitive performance does not limit long-term PA adherence in mobility-limited older adults. Additional studies in larger cohorts are warranted to verify these findings.
我们研究了基线认知表现的多个领域是否与 Lifestyle Interventions and Independence for Elders Pilot 研究(LIFE-P)中的前瞻性体力活动(PA)依从性相关。
设计、地点、参与者:LIFE-P 研究是一项针对久坐、行动受限的老年人的 PA 干预与成功老龄化教育干预的单盲、多中心、随机对照试验。
为期 12 个月的结构化、中等强度、多模式 PA 计划,包括步行、阻力训练和柔韧性练习。在前 2 个月(适应期),每周进行 3 次中心基础锻炼(40-60 分钟)。在接下来的 4 个月(过渡期),每周进行 2 次中心基础锻炼。随后的维持阶段包括可选的每周一次到两次的中心基础锻炼和家庭 PA。
在基线时进行执行和整体认知功能、工作记忆和心理运动速度的测试。中位数测试分数用于将参与者分为低或高认知表现组。
52 名行动受限的老年人(年龄:76.9±5 岁)被随机分配到 LIFE-P 的 PA 组。与认知表现较高的参与者相比,认知表现较低的参与者的 PA 依从率相似(所有 P≥0.34)。此外,认知和整体 PA 依从水平之间的所有测量值之间仅得出了较弱且无统计学意义的单变量关系(r 值范围:-0.20 至 0.12,P≥0.12)。
这些数据表明,认知表现不会限制行动受限的老年人的长期 PA 依从性。需要在更大的队列中进行更多研究来验证这些发现。