Chang Aaron J, Nomura Yohei, Barodka Viachaslau M, Hori Daijiro, Magruder Jonathan T, Katz Nevin M, Berkowitz Dan E, Hogue Charles W
From the Center for Bioengineering Innovation and Design, Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland.
Division of Cardiac Surgery, Department of Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.
Anesth Analg. 2017 Dec;125(6):1883-1886. doi: 10.1213/ANE.0000000000002217.
Acute kidney injury after cardiac surgery is associated with increased morbidity and mortality. Methods for measuring urine output in real time may better ensure renal perfusion perioperatively in contrast to the current standard of care where urine output is visually estimated after empiric epochs of time. In this study, we describe an accurate method for monitoring urine output continuously during cardiopulmonary bypass. This may provide a means for setting patient-specific targets for blood pressure and cardiopulmonary bypass flow as a potential strategy to reduce the risk for acute kidney injury.
心脏手术后的急性肾损伤与发病率和死亡率的增加相关。与目前在经验性时间段后目测估计尿量的护理标准相比,实时测量尿量的方法可能会更好地确保围手术期的肾脏灌注。在本研究中,我们描述了一种在体外循环期间连续监测尿量的准确方法。这可能为设定针对患者的血压和体外循环流量目标提供一种手段,作为降低急性肾损伤风险的潜在策略。