Department of Clinical Dietetics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
JPEN J Parenter Enteral Nutr. 2018 Feb;42(2):463-466. doi: 10.1177/0148607117699569. Epub 2017 Dec 15.
Pediatric patients with nonalcoholic fatty liver disease (NAFLD) require targeted nutrition therapy that relies on calculating energy needs. Common energy equations are inaccurate in predicting resting energy expenditure (REE), influencing total energy expenditure (TEE) estimates. Equations based on allometric scaling are simple, accurate, void of subjective activity and/or stress factor bias, and they estimate TEE.
To investigate the predictive accuracy of an allometric energy equation (AEE) in predicting TEE of children and adolescents with NAFLD.
Retrospective study performed in a single institution. The allometric equation was used to calculate AEE, and the results were compared with TEE calculated using indirect calorimetry data (measured REE) multiplied by an activity factor (AF) of 1.5 or 1.7.
Fifty-six patients with a mean age of 13 years were included in this study. The agreement between TEE (using an AF of 1.5) and AEE was -96 kcal/d (confidence interval, -29 to 221). The predictive accuracy of the allometric equation was not different between obese and nonobese patients.
Allometric equations allow for accurate estimation of TEE in children with NAFLD.
患有非酒精性脂肪性肝病（NAFLD）的儿科患者需要依赖计算能量需求的靶向营养疗法。常用的能量方程在预测静息能量消耗（REE）方面不够准确，从而影响总能量消耗（TEE）的估算。基于比例律的方程简单、准确，不存在主观活动和/或应激因素的偏差，可用于估算 TEE。
研究比例律能量方程（AEE）预测非酒精性脂肪性肝病患儿 TEE 的预测准确性。
在一家单机构进行回顾性研究。使用比例律方程计算 AEE，并将结果与间接测热法数据（实测 REE）乘以 1.5 或 1.7 的活动系数（AF）计算得出的 TEE 进行比较。
本研究纳入了 56 名平均年龄为 13 岁的患者。TEE（使用 AF 为 1.5）与 AEE 之间的一致性为-96kcal/d（置信区间，-29 至 221）。比例律方程对肥胖和非肥胖患者的 TEE 预测准确性无差异。
比例律方程可准确估算患有 NAFLD 的儿童的 TEE。
