从中国广西分离的乙型脑炎病毒株FC792的全长基因组序列
Full-Length Genome Sequence of Japanese Encephalitis Virus Strain FC792, Isolated from Guangxi, China.
作者信息
Lu Bingxia, Qin Yibin, Li Bin, He Ying, Duan Qunpeng, Liang Jiaxing, Chen Zhongwei, Su Qianlian, Bi Bingfen, Zhao Wu
机构信息
Guangxi Key Laboratory of Veterinary Biotechnology/Department of Virology, Guangxi Veterinary Research Institute, Nanning, Guangxi, China.
Guangxi Key Laboratory of Veterinary Biotechnology/Department of Virology, Guangxi Veterinary Research Institute, Nanning, Guangxi, China
出版信息
Genome Announc. 2017 Nov 30;5(48):e01054-17. doi: 10.1128/genomeA.01054-17.
We report here the complete genomic sequence of Japanese encephalitis virus (JEV) strain FC792, isolated from aborted fetuses of sows which were unimmunized with JEV vaccines in Guangxi Province, southern China. The complete JEV genome of strain FC792 had the highest nucleotide homology (99.7%) and amino acid identity (99.4%) with the sequence of JEV strain SA14-14-2 (GenBank accession number AF315119). Phylogenetic analysis showed that strain FC792 had the closest phylogenetic relationship to the sequence of strain YUNNAN0901 (GenBank accession number JQ086762). This study will help us understand the molecular pathogenesis and genetic diversity of genotype III Japanese encephalitis virus in pigs.
我们在此报告从中国南方广西省未接种日本脑炎病毒（JEV）疫苗的母猪流产胎儿中分离出的JEV毒株FC792的完整基因组序列。FC792毒株的完整JEV基因组与JEV毒株SA14 - 14 - 2（GenBank登录号AF315119）的序列具有最高的核苷酸同源性（99.7%）和氨基酸同一性（99.4%）。系统发育分析表明，FC792毒株与YUNNAN0901毒株（GenBank登录号JQ086762）的序列具有最密切的系统发育关系。本研究将有助于我们了解猪中III型日本脑炎病毒的分子发病机制和遗传多样性。
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