Frei M R, Jauchem J R, Heinmets F
Department of Biology, Trinity University, San Antonio, TX 78284.
Radiat Environ Biophys. 1989;28(1):67-77. doi: 10.1007/BF01209724.
Ketamine-anesthetized Sprague-Dawley rats were exposed in H orientation to far-field 9.3-GHz continuous-wave (CW) and pulsed (2 microseconds, 500 pps) radiofrequency radiation (RFR) at average power densities of 30 and 60 mW/cm2 (whole-body average specific absorption rates of 9.3 and 18.6 W/kg, respectively). Irradiation was conducted to cyclicly increase colonic temperature from 38.5 to 39.5 degrees C. Colonic, tympanic, and subcutaneous temperatures, ECG, blood pressure, and respiratory rate were continuously recorded during experimentation. At both power densities, the subcutaneous and tympanic temperature increases significantly exceeded the colonic temperature increase. At both exposure levels, heart rate increased significantly during irradiation and returned to baseline when exposure was discontinued. Blood pressure and respiratory rate did not significantly change during irradiation. There were no significant differences between the effects of CW and pulsed RFR exposure. The levels of subcutaneous heating and heart rate change were greater, and the times required to achieve and to recover from a 1 degree C colonic temperature increase were longer than in previous studies conducted at 2.8 GHz. Results of these studies indicate that the carrier frequency used during irradiation markedly affects the pattern of heat distribution and the physiological responses of RF-irradiated animals.
将氯胺酮麻醉的斯普拉格-道利大鼠以H方向暴露于平均功率密度为30和60 mW/cm²（全身平均比吸收率分别为9.3和18.6 W/kg）的远场9.3 GHz连续波（CW）和脉冲（2微秒，500脉冲/秒）射频辐射（RFR）中。进行辐照以使结肠温度从38.5℃循环升高至39.5℃。在实验过程中持续记录结肠、鼓膜和皮下温度、心电图、血压和呼吸频率。在两种功率密度下，皮下和鼓膜温度的升高均显著超过结肠温度的升高。在两个暴露水平下，心率在辐照期间均显著增加，停止暴露后恢复至基线水平。血压和呼吸频率在辐照期间无显著变化。连续波和脉冲射频辐射暴露的影响之间无显著差异。皮下加热和心率变化的水平更高，实现结肠温度升高1℃并恢复所需的时间比之前在2.8 GHz进行的研究更长。这些研究结果表明，辐照期间使用的载波频率显著影响热分布模式和射频辐照动物的生理反应。
